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Query: TTC3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TTC3 0 -1.128 -0.630 0.140

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TTC3 Ubiquitylation K470 -1.268 _NILEK(gl)QFSK_

Background Information for TTC3:


Pubmed-TTC3 »
Uniprot-TTC3 »
Biogrid-TTC3 »
ProteomicsDB-TTC3 »

Tumorportal-TTC3 »
COSMIC-TTC3 »
GenomeRNAi-TTC3 »
Genecards-TTC3


Protein-protein Interactions for TTC3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BACH1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf172;DSN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK2A2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CUL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ESPN Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L1BP Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait PDLIM5 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB5C Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA3C;TUBA3E Cat. description Hein, Mann, Cell 2015
Category members IP bait WAPAL Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF673 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC2LI1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TTC3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DEATH-like_dom IPR011029 1.15
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring TTC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TTC3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0045665 negative regulation of neuron differentiation Database 0.04
Category members GO Category GO:0005773 vacuole Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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