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Query: ASPM

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASPM 0 -1.997 0.390 0.300 0.580 0.002 -0.388

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ASPM Phosphorylation S392 -0.089 _DNYGLNQDLESESVNPILS(ph)PNQFLK_
ASPM Ubiquitylation K2002 -0.273 _AALLIQK(gl)YYR_
ASPM Ubiquitylation K2619 -0.325 _ETCVQAGFQDMNIKK(gl)_
ASPM Phosphorylation S605 -0.742 -0.350 _IHFS(ph)PSEPK_
ASPM Ubiquitylation K748 -0.358 _APTK(gl)EEMSLR_
ASPM Phosphorylation S425 -0.509 _VPLSNENSQVPQS(ph)PEDWRK_
ASPM Ubiquitylation K1537 -0.627 _TNYLQK(gl)R_
ASPM Ubiquitylation K2358 -0.665 _YQALK(gl)QASVVIQQQYQANR_
ASPM Ubiquitylation K2053 -1.087 -0.931 _AAVTIQSK(gl)YR_
ASPM Ubiquitylation K2823 -0.942 _AAVTIQK(gl)AFCR_
ASPM Ubiquitylation K1822 -1.087 _QLIK(gl)QQSIAALK_
ASPM Ubiquitylation K626 -1.228 _NVTTPISK(gl)R_
ASPM Ubiquitylation K1875 -1.319 _TK(gl)AAVISLQSAYR_
ASPM Ubiquitylation K2227 -1.323 _YWAMK(gl)ER_
ASPM Ubiquitylation K2045 -1.343 _IKDCNK(gl)AAVTIQSK_
ASPM Ubiquitylation K2933 -1.382 _FQEIK(gl)NSTIK_
ASPM Ubiquitylation K2021 -1.473 _TK(gl)AAVVTLQSAYR_

Background Information for ASPM:


Pubmed-ASPM »
Uniprot-ASPM »
Biogrid-ASPM »
ProteomicsDB-ASPM »

Tumorportal-ASPM »
COSMIC-ASPM »
GenomeRNAi-ASPM »
Genecards-ASPM


Protein-protein Interactions for ASPM
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASPM Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK4 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCZ Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC83 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDH5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNKSR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COPS7B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRTAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DKK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EID1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FEZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXJ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INTS4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INTU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP3K6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MXD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEUROG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OS9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PEX19 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP6R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEX13A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TP53INP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAFD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBGCP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF333 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASPM
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members P-loop_NTPase IPR027417 2.83
Category members CH-domain IPR001715 0.63
Category members CAMSAP_CH IPR022613 0.13
Category members IQ_motif_EF-hand-BS IPR000048 0


Protein complexes (CORUM database) featuring ASPM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ASPM
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0048589 developmental growth Database 0.45
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0048477 oogenesis Database 0.11
Category members GO Category GO:0045665 negative regulation of neuron differentiation Database 0.04
Category members Disease phenotype Autosomal_recessive_primary_microcephaly Autosomal recessive primary microcephaly Database 0
Category members GO Category GO:0001764 neuron migration Database 0
Category members GO Category GO:0002052 positive regulation of neuroblast proliferation Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0021873 forebrain neuroblast division Database 0
Category members GO Category GO:0051661 maintenance of centrosome location Database 0


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