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Results for the Category
Autosomal recessive primary microcephaly
(Autosomal_recessive_primary_microcephaly)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
WDR62 2
PHC1 1 -1.150 1.170 1.791 0.770
PHC1 1 1.810 -0.840 1.791 0.770
ASPM 0 0.390 0.300 0.580 0.002 -0.388
CEP152 0 -0.680 0.270
CDK6 0 -0.190 0.160
CDK6 0 -0.190 0.160 -0.510 0.013
CDK5RAP2 0 -0.900 1.740 -0.181 0.284
CASC5 0 1.010 -0.520
MCPH1 0 -0.270 -0.170
CENPJ 0 -1.550 2.060
CEP135 0 0.580 -1.210

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ASPM Phosphorylation S392 -0.089 _DNYGLNQDLESESVNPILS(ph)PNQFLK_
ASPM Phosphorylation S425 -0.509 _VPLSNENSQVPQS(ph)PEDWRK_
ASPM Phosphorylation S605 -0.742 -0.350 _IHFS(ph)PSEPK_
ASPM Ubiquitylation K626 -1.228 _NVTTPISK(gl)R_
ASPM Ubiquitylation K748 -0.358 _APTK(gl)EEMSLR_
ASPM Ubiquitylation K1537 -0.627 _TNYLQK(gl)R_
ASPM Ubiquitylation K1822 -1.087 _QLIK(gl)QQSIAALK_
ASPM Ubiquitylation K1875 -1.319 _TK(gl)AAVISLQSAYR_
ASPM Ubiquitylation K2002 -0.273 _AALLIQK(gl)YYR_
ASPM Ubiquitylation K2021 -1.473 _TK(gl)AAVVTLQSAYR_
ASPM Ubiquitylation K2045 -1.343 _IKDCNK(gl)AAVTIQSK_
ASPM Ubiquitylation K2053 -1.087 -0.931 _AAVTIQSK(gl)YR_
ASPM Ubiquitylation K2227 -1.323 _YWAMK(gl)ER_
ASPM Ubiquitylation K2358 -0.665 _YQALK(gl)QASVVIQQQYQANR_
ASPM Ubiquitylation K2619 -0.325 _ETCVQAGFQDMNIKK(gl)_
ASPM Ubiquitylation K2823 -0.942 _AAVTIQK(gl)AFCR_
ASPM Ubiquitylation K2933 -1.382 _FQEIK(gl)NSTIK_
CASC5 Phosphorylation S60 1.146 -0.112 _RVS(ph)FADTIK_
CASC5 Phosphorylation S1076 -0.351 _DVQS(ph)PGFLNEPLSSK_
CDK5RAP2 Ubiquitylation K489 -0.006 _HLTESTNQK(gl)DVLLQK_
CDK5RAP2 Phosphorylation S697 -0.007 _LAS(ph)T(ph)EQTELLASK_
CDK5RAP2 Phosphorylation T698 -0.007 _LAS(ph)T(ph)EQTELLASK_
CDK5RAP2 Ubiquitylation K943 -0.252 _SRLPILIK(gl)_
CDK5RAP2 Phosphorylation S1074 1.217 0.953 _ENPEDVLS(ph)PTSVATYLSSK_
CDK5RAP2 Phosphorylation S1238 0.477 0.111 _DLS(ph)PPRYDSLVQSQAR_
CDK5RAP2 Phosphorylation S1350 -1.016 -0.606 _IEEDNLTYQHLLPES(ph)PEPSASHALSDYETSEK_
CDK5RAP2 Phosphorylation T1885 -0.869 _GNLELRPGGAHPGT(ph)CSPSRPGS_
CDK5RAP2 Phosphorylation S1887 -0.612 -1.053 _GNLELRPGGAHPGTCS(ph)PSRPGS_
CDK5RAP2 Phosphorylation S1889 -0.312 _GNLELRPGGAHPGTCSPS(ph)RPGS_
CDK6 Ubiquitylation K3 0.121 0.039 _(ac)MEK(gl)DGLCR_
CDK6 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK6 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK6 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK6 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK6 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK6 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK6 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK6 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK6 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK6 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CENPJ Phosphorylation S260 -0.281 -0.481 _RAS(ph)PNLFSEAQYQEAPVEK_
CEP135 Phosphorylation S439 0.656 0.789 _DRS(ph)PSRLDTFLK_
CEP152 Phosphorylation T1241 -0.072 -0.258 _NKLEELQTLCKT(ph)PPR_
CEP152 Phosphorylation S1461 0.226 0.223 _NVS(ph)PEFVPCEGEGGFGLHKK_
MCPH1 Phosphorylation S333 -0.272 0.038 _YRLS(ph)PTLSSTK_
MCPH1 Phosphorylation T335 -0.306 _YRLSPT(ph)LSSTK_
PHC1 Phosphorylation T1017 -0.396 _DLGNPNTAPPT(ph)PELHGINPVFLSSNPSR_
WDR62 Phosphorylation S32 -1.724 -1.340 _RGQS(ph)SPPPAPPICLR_
WDR62 Phosphorylation S33 -0.818 -1.182 _RGQSS(ph)PPPAPPICLR_
WDR62 Phosphorylation S49 0.012 _TRLS(ph)TASEETVQNR_
WDR62 Phosphorylation S1070 0.700 _HHFETLTES(ph)PCR_
WDR62 Phosphorylation S1123 1.354 1.533 _ATQCLVKS(ph)PEVK_
WDR62 Phosphorylation T1140 0.715 1.046 _AGT(ph)GYASPDRTHVLAAGK_
WDR62 Phosphorylation S1144 0.823 1.189 _AGTGYAS(ph)PDRTHVLAAGK_
WDR62 Phosphorylation S1226 -0.377 -0.367 _S(ph)ISLGDSEGPIVATLAQPLR_
WDR62 Phosphorylation S1228 -0.358 -0.330 _SIS(ph)LGDSEGPIVATLAQPLR_
WDR62 Phosphorylation S1248 -1.061 -1.122 _RPS(ph)SVGELASLGQELQAITTATTPSLDSEGQEPALR_
WDR62 Phosphorylation S1249 -1.023 -1.122 _RPSS(ph)VGELASLGQELQAITTATT(ph)PSLDSEGQEPALR_
WDR62 Phosphorylation S1255 -1.122 _RPSSVGELAS(ph)LGQELQAITTATTPSLDSEGQEPALR_
WDR62 Phosphorylation T1268 1.841 _RPS(ph)SVGELASLGQELQAITTATT(ph)PSLDSEGQEPALR_
WDR62 Phosphorylation S1348 -1.872 _LHGSAFRPSLPAPES(ph)PGLPAHPSNPQLPEAR_


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