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Query: PHC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PHC1 1 2.165 -1.150 1.170 1.791 0.770
PHC1 1 2.165 1.810 -0.840 1.791 0.770

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PHC1 Phosphorylation T1017 -0.396 _DLGNPNTAPPT(ph)PELHGINPVFLSSNPSR_

Background Information for PHC1:


Pubmed-PHC1 »
Uniprot-PHC1 »
Biogrid-PHC1 »
ProteomicsDB-PHC1 »

Tumorportal-PHC1 »
COSMIC-PHC1 »
GenomeRNAi-PHC1 »
Genecards-PHC1


Protein-protein Interactions for PHC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait RING1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PHC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FCS IPR012313 0.31
Category members SAM IPR001660 0
Category members Znf_MYM IPR010507 0
Category members SAM_2 IPR011510 0
Category members SAM/pointed IPR013761 0
Category members SAM_type1 IPR021129 0


Protein complexes (CORUM database) featuring PHC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 116 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.56
Category members Corum 115 Polycomb repressive complex 1 (PRC1, hPRC-H) Database 1.28
Category members Corum 5513 Polycomb repressive complex Database 0.22
Category members Corum 5518 BMI1-HPH1-HPH2 complex Database 0


Categories featuring PHC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0001739 sex chromatin Database 1.47
Category members GO Category GO:0031519 PcG protein complex Database 0.62
Category members GO Category GO:0035102 PRC1 complex Database 0.62
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members Disease phenotype Autosomal_recessive_primary_microcephaly Autosomal recessive primary microcephaly Database 0
Category members GO Category GO:0071300 cellular response to retinoic acid Database 0


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