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Query: CEP135

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CEP135 0 1.445 0.580 -1.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CEP135 Phosphorylation S439 0.656 0.789 _DRS(ph)PSRLDTFLK_

Background Information for CEP135:


Pubmed-CEP135 »
Uniprot-CEP135 »
Biogrid-CEP135 »
ProteomicsDB-CEP135 »

Tumorportal-CEP135 »
COSMIC-CEP135 »
GenomeRNAi-CEP135 »
Genecards-CEP135


Protein-protein Interactions for CEP135
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PXDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C17orf59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CARD9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MIS18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDEL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TXLNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WRAP73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CEP135
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EB1_C IPR004953 0
Category members Prefoldin IPR009053 0


Protein complexes (CORUM database) featuring CEP135
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CEP135
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_727 REACTOME_MITOTIC_G2_G2_M_PHASES 0 0.46
Category members Pathway Pathway_728 REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES 0 0.4
Category members Pathway Pathway_730 REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES 0 0.33
Category members GO Category GO:0000086 G2/M transition of mitotic cell cycle Database 0.33
Category members GO Category GO:0010457 centriole-centriole cohesion Database 0.11
Category members GO Category GO:0007099 centriole replication Database 0.07
Category members Disease phenotype Autosomal_recessive_primary_microcephaly Autosomal recessive primary microcephaly Database 0
Category members GO Category GO:0005814 centriole Database 0


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