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Query: CASC5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CASC5 0 1.034 1.010 -0.520

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CASC5 Phosphorylation S60 1.146 -0.112 _RVS(ph)FADTIK_
CASC5 Phosphorylation S1076 -0.351 _DVQS(ph)PGFLNEPLSSK_

Background Information for CASC5:


Pubmed-CASC5 »
Uniprot-CASC5 »
Biogrid-CASC5 »
ProteomicsDB-CASC5 »

Tumorportal-CASC5 »
COSMIC-CASC5 »
GenomeRNAi-CASC5 »
Genecards-CASC5


Protein-protein Interactions for CASC5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BUB1B Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf172;DSN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CASC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CSNK1D Cat. description Hein, Mann, Cell 2015
Category members IP bait GAPDH Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF18A Cat. description Hein, Mann, Cell 2015
Category members IP bait MED22 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait NEK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLH Cat. description Hein, Mann, Cell 2015
Category members IP bait SART1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPC24 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZWINT Cat. description Hein, Mann, Cell 2015
Category members IP bait BUB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BUB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DSN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ETFB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NSL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PMF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP1CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPC25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VPS28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZWINT Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CASC5
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring CASC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CASC5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members GO Category GO:0034080 CENP-A containing nucleosome assembly at centromere Database 4.75
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0001675 acrosome assembly Database 0.02
Category members Disease phenotype Autosomal_recessive_primary_microcephaly Autosomal recessive primary microcephaly Database 0
Category members GO Category GO:0001669 acrosomal vesicle Database 0
Category members GO Category GO:0008608 attachment of spindle microtubules to kinetochore Database 0
Category members GO Category GO:0010923 negative regulation of phosphatase activity Database 0
Category members GO Category GO:0034501 protein localization to kinetochore Database 0
Category members GO Category GO:0071173 spindle assembly checkpoint Database 0


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