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Query: HOXC13

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HOXC13 0 0.695 0.030 0.890 -0.027 0.427
HOXC13 0 0.695 0.030 0.890 -1.413 0.651

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HOXC13 Ubiquitylation K335 0.431 0.162 _VQLK(gl)ELER_

Background Information for HOXC13:


Pubmed-HOXC13 »
Uniprot-HOXC13 »
Biogrid-HOXC13 »
ProteomicsDB-HOXC13 »

Tumorportal-HOXC13 »
COSMIC-HOXC13 »
GenomeRNAi-HOXC13 »
Genecards-HOXC13


Protein-protein Interactions for HOXC13
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HOXC13
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members Homeodomain-like IPR009057 0
Category members HoxA13_N IPR022067 0


Protein complexes (CORUM database) featuring HOXC13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HOXC13
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0009952 anterior/posterior pattern specification Database 0.06
Category members Disease phenotype Pure_hair_and_nail_ectodermal_dysplasia Pure hair and nail ectodermal dysplasia Database 0
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0001942 hair follicle development Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0035878 nail development Database 0
Category members GO Category GO:0043587 tongue morphogenesis Database 0


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