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Query: HAND2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HAND2 0 2.636 0.000 0.600

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HAND2 Ubiquitylation K183 0.800 1.236 _K(gl)ELNEILK_

Background Information for HAND2:


Pubmed-HAND2 »
Uniprot-HAND2 »
Biogrid-HAND2 »
ProteomicsDB-HAND2 »

Tumorportal-HAND2 »
COSMIC-HAND2 »
GenomeRNAi-HAND2 »
Genecards-HAND2


Protein-protein Interactions for HAND2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HAND2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members bHLH_dom IPR011598 0.32


Protein complexes (CORUM database) featuring HAND2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HAND2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0045668 negative regulation of osteoblast differentiation Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding Database 0.21
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity Database 0.18
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0001947 heart looping Database 0.08
Category members GO Category GO:0010667 negative regulation of cardiac muscle cell apoptotic process Database 0.08
Category members GO Category GO:0001967 suckling behavior Database 0.05
Category members GO Category GO:0043392 negative regulation of DNA binding Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_641 BIOCARTA_NFAT_PATHWAY 0 0
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0001525 angiogenesis Database 0
Category members GO Category GO:0003007 heart morphogenesis Database 0
Category members GO Category GO:0003219 cardiac right ventricle formation Database 0
Category members GO Category GO:0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis Database 0
Category members GO Category GO:0003266 regulation of secondary heart field cardioblast proliferation Database 0
Category members GO Category GO:0003278 apoptotic process involved in heart morphogenesis Database 0
Category members GO Category GO:0003357 noradrenergic neuron differentiation Database 0
Category members GO Category GO:0003680 AT DNA binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0007512 adult heart development Database 0
Category members GO Category GO:0010463 mesenchymal cell proliferation Database 0
Category members GO Category GO:0014032 neural crest cell development Database 0
Category members GO Category GO:0033613 activating transcription factor binding Database 0
Category members GO Category GO:0042475 odontogenesis of dentin-containing tooth Database 0
Category members GO Category GO:0042733 embryonic digit morphogenesis Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043586 tongue development Database 0
Category members GO Category GO:0046983 protein dimerization activity Database 0
Category members GO Category GO:0048485 sympathetic nervous system development Database 0
Category members GO Category GO:0048538 thymus development Database 0
Category members GO Category GO:0048935 peripheral nervous system neuron development Database 0
Category members GO Category GO:0060485 mesenchyme development Database 0
Category members GO Category GO:0060536 cartilage morphogenesis Database 0
Category members GO Category GO:0060982 coronary artery morphogenesis Database 0
Category members GO Category GO:0061032 visceral serous pericardium development Database 0
Category members GO Category GO:0061309 cardiac neural crest cell development involved in outflow tract morphogenesis Database 0
Category members GO Category GO:0061325 cell proliferation involved in outflow tract morphogenesis Database 0
Category members GO Category GO:0061371 determination of heart left/right asymmetry Database 0
Category members GO Category GO:0070888 E-box binding Database 0


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