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BIOCARTA_NFAT_PATHWAY
(Pathway_641)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
GSK3B 2 1.020 -0.870 -1.128 1.091
MAPK14 2 -0.160 -0.350
PRKAR1A 1 -0.550 0.230
PRKAR1A 1 -0.550 0.230
CSNK1A1 1 0.080 -0.140 2.048 -0.562 0.195 -0.389 0.187
RAF1 1 2.020 -1.230
CALM2 1 -0.690 0.700 1.911
CALM2 1 -0.690 0.700 0.877 -4.680
CALM3 1 -0.190 0.120 1.911
CALM3 1 -0.190 0.120 0.877 -4.680
MAP2K1 1 -1.590 2.780
PRKAR1B 1 0.660 -0.470
PRKAR1B 1 0.660 -0.470
CALM1 1 -0.440 0.360 1.911
CALM1 1 -0.440 0.360 0.877 -4.680
PRKAR2B 0 -0.290 0.380
CREBBP 0 0.840 -0.950 -3.889 -1.071
MEF2C 0 -0.980 1.550
MEF2C 0 -0.980 1.550
FKBP1A 0 -1.160 1.580
FKBP1A 0 1.040 -0.810
NFATC4 0 0.060 0.210
NFATC2 0 -0.090 0.320
MAPK3 0
PPP3CB 0 -1.240 2.140 -0.298 1.130
PPP3CB 0 -1.240 2.140 0.923 0.537
RPS6KB1 0 0.850 -0.600
PRKAR2A 0 -0.530 1.080 0.026 -1.317 -0.866 0.783 0.007
PRKAR2A 0 -0.530 1.080
PPP3CC 0 -0.380 1.050 -0.298 1.130
PPP3CC 0 -0.380 1.050 0.923 0.537
PIK3CA 0
CAMK1 0 1.160 -0.740
GATA4 0 -0.670 0.350
PPP3CA 0 1.550 -1.230 -0.298 1.130
PPP3CA 0 1.550 -1.230 0.923 0.537
AKT1 0 -0.050 0.700
AKT1 0 0.860 -0.040
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
ACTA1 0 -0.170 0.010 -0.189 0.025 -0.002 -0.165
ACTA1 0 -0.170 0.010 0.157
PIK3R1 0 1.910 -1.220 -0.441 0.147
CAMK4 0 0.780 -0.790
HAND2 0 0.000 0.600
HRAS 0 1.470 -0.520
CALR 0 -1.300 2.220 0.480 0.054
NKX2-5 0 -0.150 1.230 0.174 0.236
NKX2-5 0 -0.150 1.230 -0.123

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AKT1 Phosphorylation S124 0.252 0.311 _SGS(ph)PSDNSGAEEMEVSLAKPK_
AKT1 Phosphorylation S126 -0.241 _SGSPS(ph)DNSGAEEM(ox)EVSLAK_
AKT1 Ubiquitylation K301 0.988 _EGIK(gl)DGATMK_
CALM1 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM1 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM2 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM2 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALM3 Ubiquitylation K78 0.061 _DGDGTITTK(gl)ELGTVMR_
CALM3 Ubiquitylation K142 0.922 _VFDK(gl)DGNGYISAAELR_
CALR Ubiquitylation K48 0.703 _SDFGK(gl)FVLSSGK_
CALR Ubiquitylation K153 -0.924 0.619 _GK(gl)NVLINK_
CALR Ubiquitylation K159 -1.004 0.381 _NVLINK(gl)DIR_
CAMK1 Ubiquitylation K49 -0.158 _LVAIK(gl)CIAK_
CAMK4 Phosphorylation S360 -0.256 0.086 _DPS(ph)PIQDGNEDMK_
CREBBP Phosphorylation S2093 0.037 0.097 _SIS(ph)PSALQDLLR_
CSNK1A1 Ubiquitylation K8 -0.342 -0.408 _(ac)ASSSGSK(gl)AEFIVGGK_
CSNK1A1 Ubiquitylation K18 0.772 _AEFIVGGKYK(gl)_
CSNK1A1 Ubiquitylation K225 0.039 0.502 _TSLPWQGLK(gl)AATK_
CSNK1A1 Ubiquitylation K304 -0.489 0.015 _QK(gl)AAQQAASSSGQGQQAQTPTGK_
FKBP1A Ubiquitylation K72 1.074 _RGQTCVVHYTGM(ox)LEDGK(gl)K_
FKBP1A Ubiquitylation K73 0.453 _RGQTCVVHYTGM(ox)LEDGK(gl)K_
FKBP1A Ubiquitylation K90 0.605 1.010 _FM(ox)LGK(gl)QEVIR_
GATA4 Phosphorylation S109 -0.520 -0.425 _FS(ph)FPGTTGSLAAAAAAAAAR_
GATA4 Phosphorylation S407 -0.185 0.124 _LS(ph)PQGYASPVSQSPQTSSK_
GSK3B Phosphorylation S9 -0.483 0.010 _TTS(ph)FAESCKPVQQPSAFGSMK_
GSK3B Ubiquitylation K85 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Ubiquitylation K86 -0.204 _LCDSGELVAIK(gl)K_
GSK3B Phosphorylation S215 0.296 0.477 _GEPNVS(ph)YICSR_
GSK3B Phosphorylation Y216 0.356 0.376 _GEPNVSY(ph)ICSR_
GSK3B Phosphorylation T390 2.800 2.527 _IQAAAST(ph)PTNATAASDANTGDR_
HAND2 Ubiquitylation K183 0.800 1.236 _K(gl)ELNEILK_
HRAS Ubiquitylation K170 -1.005 _K(gl)LNPPDESGPGCMSCK_
MAP2K1 Ubiquitylation K192 -0.205 -0.241 _DVK(gl)PSNILVNSR_
MAP2K1 Phosphorylation S385 0.066 _RSDAEEVDFAGWLCSTIGLNQPS(ph)TPTHAAGV_
MAP2K1 Phosphorylation T386 0.377 _RSDAEEVDFAGWLCSTIGLNQPST(ph)PTHAAGV_
MAPK14 Phosphorylation S2 3.221 3.623 _(ac)S(ph)QERPTFYR_
MAPK14 Phosphorylation T180 0.958 1.087 _HTDDEM(ox)T(ph)GYVATR_
MAPK14 Phosphorylation Y182 1.388 1.374 _HTDDEM(ox)TGY(ph)VATR_
MAPK14 Ubiquitylation K249 0.073 -1.380 _LVGTPGAELLKK(gl)_
MAPK3 Phosphorylation Y204 -0.807 -2.487 _IADPEHDHTGFLTEY(ph)VATR_
MAPK3 Ubiquitylation K289 -0.608 _NYLQSLPSKTK(gl)_
MEF2C Ubiquitylation K23 -0.140 _QVTFTK(gl)R_
MEF2C Phosphorylation S240 0.008 0.302 _NS(ph)PGLLVSPGNLNK_
MEF2C Phosphorylation S406 0.272 0.338 _SEPVS(ph)PPRDR_
NFATC2 Phosphorylation S53 -0.845 -1.099 _VAS(ph)PPSGPAYPDDVLDYGLKPYSPLASLSGEPPGR_
NFATC2 Phosphorylation T325 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
NFATC2 Phosphorylation S326 -0.605 0.168 _T(ph)SPDPSPVSAAPSK_
NFATC4 Phosphorylation S289 -1.594 -0.700 _RGS(ph)LGEEGSEPPPPPPLPLAR_
NFATC4 Phosphorylation S311 0.305 _DPGS(ph)PGPFDYVGAPPAESIPQK_
NFATC4 Phosphorylation S334 0.917 0.074 _RTS(ph)SEQAVALPR_
PIK3CA Ubiquitylation K864 0.390 0.588 _NSHTIM(ox)QIQCK(gl)GGLK_
PIK3CA Ubiquitylation K868 0.204 0.651 _NSHTIM(ox)QIQCKGGLK(gl)_
PIK3CA Ubiquitylation K974 -0.273 _GAQECTK(gl)TREFER_
PPP3CA Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CA Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CA Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CA Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CB Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CB Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CB Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CB Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PPP3CC Ubiquitylation K32 -0.137 _LTAK(gl)EVFDNDGKPR_
PPP3CC Ubiquitylation K56 0.132 _VDVLK(gl)NHLVK_
PPP3CC Ubiquitylation K323 0.705 _AAVLK(gl)YENNVMNIR_
PPP3CC Ubiquitylation K405 0.078 _AIGK(gl)MAR_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
PRKAR1A Ubiquitylation K63 -1.895 _LEKEEAK(gl)QIQNLQK_
PRKAR1A Ubiquitylation K70 -0.869 0.073 _QIQNLQK(gl)AGTR_
PRKAR1A Phosphorylation S83 -0.969 -0.776 _EDEIS(ph)PPPPNPVVK_
PRKAR1A Ubiquitylation K92 -3.269 -2.395 _TDSREDEISPPPPNPVVK(gl)GR_
PRKAR1A Ubiquitylation K222 0.412 0.536 _TNVK(gl)LWGIDR_
PRKAR1A Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1A Ubiquitylation K261 -0.886 _VSILESLDK(gl)WER_
PRKAR1A Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1A Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR1A Ubiquitylation K367 -0.939 0.044 _VLGPCSDILK(gl)R_
PRKAR1B Phosphorylation S3 0.185 0.343 _(ac)AS(ph)PPACPSEEDESLKGCELYVQLHGIQQVLK_
PRKAR1B Ubiquitylation K244 -0.384 3.721 _K(gl)MYEEFLSK_
PRKAR1B Ubiquitylation K346 0.329 _GPLK(gl)CVK_
PRKAR1B Ubiquitylation K349 -0.425 -0.103 _CVK(gl)LDRPR_
PRKAR2A Phosphorylation S99 0.020 0.056 _RVS(ph)VCAETYNPDEEEEDTDPR_
PRKAR2A Phosphorylation T104 -0.175 _RVSVCAET(ph)YNPDEEEEDTDPR_
PRKAR2A Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
PRKAR2B Phosphorylation T69 -0.367 _TWGDLGAAAGGGT(ph)PSK_
PRKAR2B Phosphorylation S114 0.366 0.525 _RAS(ph)VCAEAYNPDEEEDDAESR_
PRKAR2B Ubiquitylation K359 0.640 _GQYFGELALVTNK(gl)PR_
RAF1 Phosphorylation S29 0.028 -0.571 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation T31 0.028 -0.669 _DAVFDGSSCIS(ph)PTIVQQFGYQR_
RAF1 Phosphorylation S244 0.053 _YSTPHAFTFNTSS(ph)PSSEGSLSQR_
RAF1 Phosphorylation S259 -0.069 0.054 _STS(ph)TPNVHM(ox)VSTTLPVDSR_
RAF1 Phosphorylation S301 -0.651 _SHSESASPSALSSSPNNLS(ph)PTGWSQPK_
RAF1 Phosphorylation T303 -0.664 _SHSESASPSALSSSPNNLSPT(ph)GWSQPK_
RAF1 Phosphorylation S497 -0.449 _SRWS(ph)GSQQVEQPTGSVLWMAPEVIR_
RAF1 Phosphorylation S621 0.212 0.271 _SAS(ph)EPSLHR_
RAF1 Phosphorylation S642 -0.197 0.463 _AAHTEDINACTLTTS(ph)PR_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_


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