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Query: NFATC4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFATC4 0 1.432 0.060 0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFATC4 Phosphorylation S311 0.305 _DPGS(ph)PGPFDYVGAPPAESIPQK_
NFATC4 Phosphorylation S334 0.917 0.074 _RTS(ph)SEQAVALPR_
NFATC4 Phosphorylation S289 -1.594 -0.700 _RGS(ph)LGEEGSEPPPPPPLPLAR_

Background Information for NFATC4:


Pubmed-NFATC4 »
Uniprot-NFATC4 »
Biogrid-NFATC4 »
ProteomicsDB-NFATC4 »

Tumorportal-NFATC4 »
COSMIC-NFATC4 »
GenomeRNAi-NFATC4 »
Genecards-NFATC4


Protein-protein Interactions for NFATC4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PPP3CA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPP3CC Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NFATC4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members IPT IPR002909 0.11
Category members NFAT IPR008366 0
Category members p53-like_TF_DNA-bd IPR008967 0
Category members RHD IPR011539 0
Category members Ig_E-set IPR014756 0


Protein complexes (CORUM database) featuring NFATC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NFATC4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage Database 1.14
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0034644 cellular response to UV Database 0.49
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members Pathway Pathway_587 KEGG_T_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.25
Category members Pathway Pathway_648 KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY 0 0.19
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members Pathway Pathway_686 BIOCARTA_BCR_PATHWAY 0 0.16
Category members GO Category GO:0048167 regulation of synaptic plasticity Database 0.14
Category members Pathway Pathway_532 PID_ERBB2_ERBB3_PATHWAY 0 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Pathway Pathway_698 BIOCARTA_CALCINEURIN_PATHWAY 0 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0042975 peroxisome proliferator activated receptor binding Database 0.05
Category members Pathway Pathway_1034 KEGG_AXON_GUIDANCE 0 0.04
Category members Pathway Pathway_543 BIOCARTA_TCR_PATHWAY 0 0.03
Category members Pathway Pathway_218 BIOCARTA_GPCR_PATHWAY 0 0
Category members Pathway Pathway_436 KEGG_VEGF_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_524 BIOCARTA_FMLP_PATHWAY 0 0
Category members Pathway Pathway_597 BIOCARTA_FCER1_PATHWAY 0 0
Category members Pathway Pathway_641 BIOCARTA_NFAT_PATHWAY 0 0
Category members Pathway Pathway_646 KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY 0 0
Category members Pathway Pathway_715 KEGG_MAPK_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0001569 patterning of blood vessels Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007507 heart development Database 0
Category members GO Category GO:0032760 positive regulation of tumor necrosis factor production Database 0
Category members GO Category GO:0045333 cellular respiration Database 0
Category members GO Category GO:0051145 smooth muscle cell differentiation Database 0
Category members GO Category GO:0055001 muscle cell development Database 0
Category members GO Category GO:0071285 cellular response to lithium ion Database 0


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