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Query: DLX5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DLX5 0 0.033 -0.590 0.650 -1.286 0.204

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DLX5 Phosphorylation S225 -0.821 _SGEIPSEQHPGAS(ph)AS(ph)PPCASPPVSAPASWDFGVPQR_
DLX5 Phosphorylation S227 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_
DLX5 Phosphorylation S232 -1.137 _SGEIPSEQHPGASAS(ph)PPCAS(ph)PPVSAPASWDFGVPQR_

Background Information for DLX5:





Protein-protein Interactions for DLX5

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in DLX5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Homeobox_dom IPR001356 0.63
Category members HTH_motif IPR000047 0.39
Category members Homeobox_metazoa IPR020479 0.28
Category members Homeodomain-like IPR009057 0
Category members Distal-less_N IPR022135 0


Protein complexes (CORUM database) featuring DLX5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DLX5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0050679 positive regulation of epithelial cell proliferation Database 0.5
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0030855 epithelial cell differentiation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0060322 head development Database 0.27
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0030509 BMP signaling pathway Database 0.2
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0060349 bone morphogenesis Database 0.17
Category members GO Category GO:0007411 axon guidance Database 0.13
Category members GO Category GO:0007409 axonogenesis Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0001958 endochondral ossification Database 0.04
Category members GO Category GO:0048646 anatomical structure formation involved in morphogenesis Database 0.04
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_209 PID_DELTA_NP63_PATHWAY 0 0
Category members Disease phenotype Split_hand-split_foot_malformation Split hand-split foot malformation Database 0
Category members GO Category GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding Database 0
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0001501 skeletal system development Database 0
Category members GO Category GO:0001649 osteoblast differentiation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007399 nervous system development Database 0
Category members GO Category GO:0030326 embryonic limb morphogenesis Database 0
Category members GO Category GO:0042472 inner ear morphogenesis Database 0
Category members GO Category GO:0043583 ear development Database 0
Category members GO Category GO:0045669 positive regulation of osteoblast differentiation Database 0
Category members GO Category GO:0060166 olfactory pit development Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0


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