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Query: PLSCR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PLSCR1 0 -0.599 -0.520 0.570

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PLSCR1 Ubiquitylation K223 -0.674 -0.495 _FTIQNEK(gl)REDVLK_

Background Information for PLSCR1:


Pubmed-PLSCR1 »
Uniprot-PLSCR1 »
Biogrid-PLSCR1 »
ProteomicsDB-PLSCR1 »

Tumorportal-PLSCR1 »
COSMIC-PLSCR1 »
GenomeRNAi-PLSCR1 »
Genecards-PLSCR1


Protein-protein Interactions for PLSCR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BOLA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf49 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLCC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM134C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM8A1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait REEP5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RTN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM128 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PLSCR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Scramblase IPR005552 0.48
Category members Tubby_C-like IPR025659 0.07


Protein complexes (CORUM database) featuring PLSCR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PLSCR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0017128 phospholipid scramblase activity Database 0.48
Category members GO Category GO:0031012 extracellular matrix Database 0.45
Category members GO Category GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0017121 phospholipid scrambling Database 0.2
Category members GO Category GO:0030168 platelet activation Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0045121 membrane raft Database 0.11
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0051607 defense response to virus Database 0.07
Category members GO Category GO:0045089 positive regulation of innate immune response Database 0.05
Category members GO Category GO:0035456 response to interferon-beta Database 0.03
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0005154 epidermal growth factor receptor binding Database 0
Category members GO Category GO:0006659 phosphatidylserine biosynthetic process Database 0
Category members GO Category GO:0006953 acute-phase response Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0033003 regulation of mast cell activation Database 0
Category members GO Category GO:0042609 CD4 receptor binding Database 0
Category members GO Category GO:0045071 negative regulation of viral genome replication Database 0


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