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Query: HNRNPK

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HNRNPK 0 3.145 -0.160 0.450
HNRNPK 0 3.145 -0.160 0.450 -0.273 -1.081 -0.609 -0.231 -0.195

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HNRNPK Ubiquitylation K52 1.081 1.257 _ILLQSK(gl)NAGAVIGK_
HNRNPK Ubiquitylation K63 -0.065 0.839 _NAGAVIGK(gl)GGK(gl)NIK_
HNRNPK Ubiquitylation K405 0.830 0.378 _DLAGSIIGK(gl)GGQR_
HNRNPK Phosphorylation S116 0.499 0.377 _IIPTLEEGLQLPS(ph)PTATSQLPLESDAVECLNYQHYK_
HNRNPK Phosphorylation T120 0.365 _IIPTLEEGLQLPSPTAT(ph)SQLPLESDAVECLNYQHYK_
HNRNPK Phosphorylation S379 -0.481 0.342 _GS(ph)YGDLGGPIITTQVTIPK_
HNRNPK Phosphorylation S216 0.474 0.302 _IILDLISES(ph)PIK_
HNRNPK Ubiquitylation K219 -0.125 0.098 _IILDLISESPIK(gl)GR_
HNRNPK Ubiquitylation K198 -0.013 0.077 _VVLIGGK(gl)PDR_
HNRNPK Ubiquitylation K34 -0.398 0.033 _RPAEDMEEEQAFK(gl)R_
HNRNPK Phosphorylation S284 0.141 -0.133 _RDYDDMS(ph)PR_
HNRNPK Ubiquitylation K179 -0.020 -0.161 _ENTQTTIK(gl)LFQECCPHSTDR_
HNRNPK Ubiquitylation K60 0.068 _NAGAVIGK(gl)GGK(gl)NIK_
HNRNPK Phosphorylation T118 0.679 _KIIPTLEEGLQLPSPT(ph)ATSQLPLESDAVECLNYQHYK_
HNRNPK Ubiquitylation K163 0.329 _LLIHQSLAGGIIGVK(gl)GAK_

Background Information for HNRNPK:


Pubmed-HNRNPK »
Uniprot-HNRNPK »
Biogrid-HNRNPK »
ProteomicsDB-HNRNPK »

Tumorportal-HNRNPK »
COSMIC-HNRNPK »
GenomeRNAi-HNRNPK »
Genecards-HNRNPK


Protein-protein Interactions for HNRNPK
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FUS Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPH2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MATR3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait TAF15 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNX9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRMT61B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HNRNPK
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom_type_2 IPR004044 0.34
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring HNRNPK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1181 C complex spliceosome Database 2.39
Category members Corum 5615 Emerin complex 52 Database 0.99
Category members Corum 5613 Emerin complex 25 Database 0.04


Categories featuring HNRNPK
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0071013 catalytic step 2 spliceosome Database 2.28
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0002102 podosome Database 0.3
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding Database 0
Category members GO Category GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0010988 regulation of low-density lipoprotein particle clearance Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0042995 cell projection Database 0
Category members GO Category GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process Database 0
Category members GO Category GO:0048260 positive regulation of receptor-mediated endocytosis Database 0


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