Results for the Category
regulation of protein stability
(GO:0031647)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| TRIM24 | 2 | 0.580 | -0.300 | -1.173 | -0.067 | -0.484 | -0.364 | |
| CDC42 | 0 | -0.170 | 0.490 | -0.597 | -1.527 | -1.013 | ||
| CDC42 | 0 | 1.240 | -0.940 | -0.597 | -1.527 | -1.013 | ||
| AURKA | 0 | -0.450 | -0.060 | -2.905 | -1.603 | |||
| FBXO7 | 0 | 1.380 | -0.260 | -0.647 | ||||
| TADA2A | 0 | |||||||
| GIPC1 | 0 | 0.050 | -0.100 | |||||
| SOX4 | 0 | 1.610 | -0.930 | |||||
| USP3 | 0 | 0.220 | -0.540 | |||||
| ANK2 | 0 | 0.370 | -0.920 | |||||
| CDKN2A | 0 | -0.080 | -0.260 | -0.556 | -1.080 | -3.270 | -1.110 | |
| CDKN2AIP | 0 | 0.810 | -0.640 | -2.486 | -0.718 | 0.428 | ||
| BCL2 | 0 | 0.910 | -0.740 | |||||
| USP19 | 0 | -0.550 | 0.450 | -3.664 | -0.183 | |||
| DPM3 | 0 | 0.350 | -0.390 | 0.453 | 0.384 | |||
| ASPH | 0 | 0.610 | -0.900 | -0.983 | -0.025 | 0.915 | 0.710 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ANK2 | Phosphorylation | S1459 | 0.673 | 0.675 | _ES(ph)ESDQEQEEEIDM(ox)TSEK_ |
| ANK2 | Phosphorylation | S1461 | 0.678 | 0.687 | _ESES(ph)DQEQEEEIDMTSEK_ |
| ANK2 | Phosphorylation | S3793 | 0.342 | 0.385 | _AMIVPSS(ph)PSK_ |
| ANK2 | Phosphorylation | S3823 | -0.465 | -0.203 | _GGS(ph)PIIQEPEEPSEHREESSPR_ |
| ANK2 | Phosphorylation | T3844 | 0.389 | _T(ph)SLVIVESADNQPETCER_ | |
| ANK2 | Phosphorylation | S3845 | 0.659 | 0.389 | _KTS(ph)LVIVESADNQPETCER_ |
| BCL2 | Ubiquitylation | K22 | 1.480 | _YIHYK(gl)LSQR_ | |
| CDC42 | Ubiquitylation | K173 | -1.839 | _DDPSTIEK(gl)LAK_ | |
| CDC42 | Ubiquitylation | K178 | -0.801 | -0.716 | _NK(gl)QKPITPETAEK_ |
| CDC42 | Ubiquitylation | K180 | -1.806 | _QK(gl)PITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K189 | -1.082 | _QKPITPETAEK(gl)LAR_ | |
| CDC42 | Ubiquitylation | K198 | 0.550 | 1.159 | _AVK(gl)YVECSALTQK_ |
| CDC42 | Ubiquitylation | K208 | -0.937 | 0.038 | _YVECSALTQK(gl)GLK_ |
| CDC42 | Ubiquitylation | K228 | -2.488 | _NVFDEAILAALEPPEPK(gl)K_ | |
| CDC42 | Ubiquitylation | K229 | -1.254 | _NVFDEAILAALEPPEPKK(gl)_ | |
| FBXO7 | Ubiquitylation | K393 | -0.096 | _VQDTDWK(gl)ELYR_ | |
| GIPC1 | Ubiquitylation | K80 | 0.463 | _IEGFTNVK(gl)ELYGK_ | |
| GIPC1 | Ubiquitylation | K199 | -0.691 | -0.589 | _LLK(gl)ELPR_ |
| GIPC1 | Ubiquitylation | K210 | -0.064 | _TFTLK(gl)LTEPR_ | |
| SOX4 | Phosphorylation | S354 | -0.003 | _SSAASSPAAGRS(ph)PADHR_ | |
| TADA2A | Ubiquitylation | K407 | -1.091 | _SALLNECNK(gl)QGGLR_ | |
| TRIM24 | Ubiquitylation | K303 | 0.293 | _IIEVNQNQK(gl)QVEQDIK_ | |
| TRIM24 | Ubiquitylation | K341 | 1.339 | _MK(gl)LMQQQQEVAGLSK_ | |
| TRIM24 | Phosphorylation | S660 | -0.300 | _TVQS(ph)PNSSVPSPGLAGPVTMTSVHPPIR_ | |
| TRIM24 | Phosphorylation | S768 | 2.572 | _SILTSLLLNSS(ph)QSSTSEETVLR_ | |
| TRIM24 | Phosphorylation | S771 | 3.067 | _SILTSLLLNSSQSS(ph)TSEETVLR_ | |
| TRIM24 | Phosphorylation | S808 | 0.469 | _SEWLDPS(ph)QKSPLHVGETR_ | |
| TRIM24 | Phosphorylation | S811 | 0.564 | 0.219 | _SEWLDPSQKS(ph)PLHVGETR_ |
| TRIM24 | Phosphorylation | S1042 | 2.366 | 1.350 | _LKS(ph)IEER_ |
| USP3 | Ubiquitylation | K354 | -0.895 | _SK(gl)NQENGPVCSLR_ | |
| USP3 | Ubiquitylation | K423 | -0.875 | _NK(gl)VDTYVEFPLR_ |
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