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bioLOGIC Data

Query: DPM3

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
DPM3	0	0.837	0.350	-0.390				0.453	0.384

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence

Background Information for DPM3:

Pubmed-DPM3 »

Uniprot-DPM3 »

Biogrid-DPM3 »

ProteomicsDB-DPM3 »

Tumorportal-DPM3 »

COSMIC-DPM3 »

GenomeRNAi-DPM3 »

Genecards-DPM3

Protein-protein Interactions for DPM3

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait CEP250	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NEK1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NRIP3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PPP2R1A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TFG	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TGS1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait TINF2	Cat. description	Hein, Mann, Cell 2015

Protein Domains in DPM3

	Domain name	Domain Description	TC-NER relevance -log10(p-value)

Protein complexes (CORUM database) featuring DPM3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	5244	Dolichol-phosphate mannose (DPM) synthase	Database	0

Categories featuring DPM3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	Pathway	Pathway_11	REACTOME_METABOLISM_OF_PROTEINS	0	12.01
Category members	GO Category	GO:0044267	cellular protein metabolic process	Database	10.42
Category members	GO Category	GO:0005789	endoplasmic reticulum membrane	Database	1.57
Category members	GO Category	GO:0005783	endoplasmic reticulum	Database	0.62
Category members	GO Category	GO:0006488	dolichol-linked oligosaccharide biosynthetic process	Database	0.28
Category members	GO Category	GO:0031647	regulation of protein stability	Database	0.21
Category members	Pathway	Pathway_93	REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN	0	0.18
Category members	GO Category	GO:0006501	C-terminal protein lipidation	Database	0.1
Category members	GO Category	GO:0005975	carbohydrate metabolic process	Database	0.07
Category members	Pathway	Pathway_461	REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS	0	0.04
Category members	Pathway	Pathway_109	KEGG_N_GLYCAN_BIOSYNTHESIS	0	0.04
Category members	Pathway	Pathway_92	REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS	0	0
Category members	Pathway	Pathway_94	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	0	0
Category members	Pathway	Pathway_95	REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION	0	0
Category members	GO Category	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity	Database	0
Category members	GO Category	GO:0006506	GPI anchor biosynthetic process	Database	0
Category members	GO Category	GO:0018279	protein N-linked glycosylation via asparagine	Database	0
Category members	GO Category	GO:0030176	integral to endoplasmic reticulum membrane	Database	0
Category members	GO Category	GO:0033185	dolichol-phosphate-mannose synthase complex	Database	0
Category members	GO Category	GO:0035268	protein mannosylation	Database	0
Category members	GO Category	GO:0035269	protein O-linked mannosylation	Database	0
Category members	GO Category	GO:0043687	post-translational protein modification	Database	0