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Query: USP3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP3 0 -1.770 0.220 -0.540

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP3 Ubiquitylation K423 -0.875 _NK(gl)VDTYVEFPLR_
USP3 Ubiquitylation K354 -0.895 _SK(gl)NQENGPVCSLR_

Background Information for USP3:


Pubmed-USP3 »
Uniprot-USP3 »
Biogrid-USP3 »
ProteomicsDB-USP3 »

Tumorportal-USP3 »
COSMIC-USP3 »
GenomeRNAi-USP3 »
Genecards-USP3


Protein-protein Interactions for USP3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ISLR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NT5E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait USP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Znf_UBP IPR001607 0.05


Protein complexes (CORUM database) featuring USP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0031647 regulation of protein stability Database 0.21
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0016578 histone deubiquitination Database 0


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