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Query: TRIM24

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TRIM24 2 4.890 0.580 -0.300 -1.173 -0.067 -0.484 -0.364

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TRIM24 Phosphorylation S768 2.572 _SILTSLLLNSS(ph)QSSTSEETVLR_
TRIM24 Phosphorylation S1042 2.366 1.350 _LKS(ph)IEER_
TRIM24 Phosphorylation S808 0.469 _SEWLDPS(ph)QKSPLHVGETR_
TRIM24 Phosphorylation S811 0.564 0.219 _SEWLDPSQKS(ph)PLHVGETR_
TRIM24 Phosphorylation S660 -0.300 _TVQS(ph)PNSSVPSPGLAGPVTMTSVHPPIR_
TRIM24 Ubiquitylation K303 0.293 _IIEVNQNQK(gl)QVEQDIK_
TRIM24 Ubiquitylation K341 1.339 _MK(gl)LMQQQQEVAGLSK_
TRIM24 Phosphorylation S771 3.067 _SILTSLLLNSSQSS(ph)TSEETVLR_

Background Information for TRIM24:


Pubmed-TRIM24 »
Uniprot-TRIM24 »
Biogrid-TRIM24 »
ProteomicsDB-TRIM24 »

Tumorportal-TRIM24 »
COSMIC-TRIM24 »
GenomeRNAi-TRIM24 »
Genecards-TRIM24


Protein-protein Interactions for TRIM24
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TRIM33 Cat. description Hein, Mann, Cell 2015
Category members IP bait C22orf41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC16 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNKSR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait QPRT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RFPL4B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDYHV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF133 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF254 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF264 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF324B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF331 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF483 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF550 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF695 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF764 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TRIM24
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members Bbox_C IPR003649 0.18
Category members Znf_B-box IPR000315 0
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring TRIM24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring TRIM24
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members Pathway Pathway_265 REACTOME_SIGNALING_BY_FGFR_IN_DISEASE 0 1.42
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_559 REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS 0 1.1
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0016922 ligand-dependent nuclear receptor binding Database 0.89
Category members GO Category GO:0070577 histone acetyl-lysine binding Database 0.88
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members Disease phenotype THYROID_CARCINOMA_PAPILLARY THYROID CARCINOMA PAPILLARY Database 0.72
Category members Pathway Pathway_592 REACTOME_SIGNALING_BY_FGFR1_MUTANTS 0 0.4
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members Pathway Pathway_528 REACTOME_SIGNALING_BY_FGFR_MUTANTS 0 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0046777 protein autophosphorylation Database 0.23
Category members GO Category GO:0031647 regulation of protein stability Database 0.21
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0005719 nuclear euchromatin Database 0.15
Category members GO Category GO:0071391 cellular response to estrogen stimulus Database 0.12
Category members Disease phenotype Papillary_or_follicular_thyroid_carcinoma Papillary or follicular thyroid carcinoma Database 0.09
Category members GO Category GO:0005726 perichromatin fibrils Database 0.09
Category members GO Category GO:0070562 regulation of vitamin D receptor signaling pathway Database 0.07
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0010628 positive regulation of gene expression Database 0
Category members GO Category GO:0034056 estrogen response element binding Database 0
Category members GO Category GO:0043434 response to peptide hormone Database 0
Category members GO Category GO:0055074 calcium ion homeostasis Database 0


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