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Query: USP19

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP19 0 -3.397 -0.550 0.450 -3.664 -0.183

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for USP19:


Pubmed-USP19 »
Uniprot-USP19 »
Biogrid-USP19 »
ProteomicsDB-USP19 »

Tumorportal-USP19 »
COSMIC-USP19 »
GenomeRNAi-USP19 »
Genecards-USP19


Protein-protein Interactions for USP19
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AURKC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FERD3L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IRF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SKP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in USP19
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members CS_dom IPR007052 0.57
Category members Peptidase_C19_UCH IPR001394 0.53
Category members HSP20-like_chaperone IPR008978 0.18
Category members Znf_MYND IPR002893 0.06


Protein complexes (CORUM database) featuring USP19
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP19
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0030433 ER-associated ubiquitin-dependent protein catabolic process Database 0.33
Category members GO Category GO:0031647 regulation of protein stability Database 0.21
Category members GO Category GO:0034976 response to endoplasmic reticulum stress Database 0.06
Category members GO Category GO:0014732 skeletal muscle atrophy Database 0.05
Category members GO Category GO:0008234 cysteine-type peptidase activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0048642 negative regulation of skeletal muscle tissue development Database 0


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