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Query: ASPH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASPH 0 0.617 0.610 -0.900 -0.983 -0.025 0.915 0.710

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ASPH:


Pubmed-ASPH »
Uniprot-ASPH »
Biogrid-ASPH »
ProteomicsDB-ASPH »

Tumorportal-ASPH »
COSMIC-ASPH »
GenomeRNAi-ASPH »
Genecards-ASPH


Protein-protein Interactions for ASPH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ASPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BCHE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD93 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBLN7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-E Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYZL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NELL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PVRL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VTI1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDYHV1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASPH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Asp_Arg_Pro-Hydrxlase IPR007803 0.1
Category members Asp-B-hydro/Triadin_dom IPR007943 0


Protein complexes (CORUM database) featuring ASPH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ASPH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0070588 calcium ion transmembrane transport Database 0.25
Category members GO Category GO:0010649 regulation of cell communication by electrical coupling Database 0.23
Category members GO Category GO:0060021 palate development Database 0.23
Category members GO Category GO:0034704 calcium channel complex Database 0.21
Category members GO Category GO:0031647 regulation of protein stability Database 0.21
Category members GO Category GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity Database 0.19
Category members GO Category GO:0007389 pattern specification process Database 0.18
Category members GO Category GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Database 0.12
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0018193 peptidyl-amino acid modification Database 0.1
Category members GO Category GO:0005513 detection of calcium ion Database 0.1
Category members GO Category GO:0014701 junctional sarcoplasmic reticulum membrane Database 0.06
Category members GO Category GO:0033198 response to ATP Database 0.04
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Pathway Pathway_407 BIOCARTA_HIF_PATHWAY 0 0
Category members GO Category GO:0006936 muscle contraction Database 0
Category members GO Category GO:0008307 structural constituent of muscle Database 0
Category members GO Category GO:0010524 positive regulation of calcium ion transport into cytosol Database 0
Category members GO Category GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Database 0
Category members GO Category GO:0030176 integral to endoplasmic reticulum membrane Database 0
Category members GO Category GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity Database 0
Category members GO Category GO:0032237 activation of store-operated calcium channel activity Database 0
Category members GO Category GO:0032541 cortical endoplasmic reticulum Database 0
Category members GO Category GO:0033017 sarcoplasmic reticulum membrane Database 0
Category members GO Category GO:0033018 sarcoplasmic reticulum lumen Database 0
Category members GO Category GO:0035108 limb morphogenesis Database 0
Category members GO Category GO:0042264 peptidyl-aspartic acid hydroxylation Database 0
Category members GO Category GO:0045862 positive regulation of proteolysis Database 0
Category members GO Category GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity Database 0
Category members GO Category GO:0060325 face morphogenesis Database 0
Category members GO Category GO:0071277 cellular response to calcium ion Database 0


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