bioLOGIC Category
Results for the Category
DNA damage response, detection of DNA damage
(GO:0042769)
RNAi screen result
|
RNAPII IP (MG132) |
CSB IP |
CSB IP (MG132) |
Chrom. |
Chrom. (MG132) |
Ubi /Phospo |
Ubi /Phospho (MG132) |
W |
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|
Gene name |
MGoogle Score |
RNAi high |
RNAi low |
RNAPII-IP (MG132) |
CSB-IP |
CSB-IP (MG132) |
Chrom. |
Chrom. (MG132) |
PARP1
|
2
|
|
|
|
|
|
|
|
PARP1
|
2
|
|
|
-0.200
|
0.357
|
0.412
|
0.442
|
0.293
|
PNKP
|
0
|
1.170
|
-0.260
|
-1.642
|
|
|
0.133
|
0.861
|
MRPS35
|
0
|
1.280
|
-0.610
|
0.505
|
-0.159
|
0.238
|
0.493
|
0.037
|
SOX4
|
0
|
1.610
|
-0.930
|
|
|
|
|
|
MRPS26
|
0
|
1.270
|
-0.850
|
0.969
|
0.131
|
0.402
|
0.440
|
0.890
|
MRPS9
|
0
|
1.070
|
-0.790
|
0.356
|
0.010
|
0.215
|
0.495
|
0.019
|
HMGA2
|
0
|
0.340
|
-0.490
|
|
|
|
|
|
MRPS11
|
0
|
-0.590
|
0.670
|
|
0.083
|
0.230
|
0.255
|
|
Gene name |
PTM type |
PTM site |
UV |
UV (MG132) |
Sequence |
HMGA2
|
Phosphorylation
|
S44
|
-0.564
|
-0.762
|
_KQQQEPTGEPS(ph)PK_
|
HMGA2
|
Phosphorylation
|
S105
|
-0.055
|
-0.046
|
_KPAQEETEETSSQES(ph)AEED_
|
MRPS9
|
Ubiquitylation
|
K253
|
|
-0.988
|
_SVTLESK(gl)K_
|
MRPS9
|
Ubiquitylation
|
K254
|
|
-0.336
|
_SVTLESKK(gl)_
|
PARP1
|
Phosphorylation
|
S41
|
|
-0.803
|
_MAIMVQS(ph)PMFDGK_
|
PARP1
|
Ubiquitylation
|
K84
|
1.223
|
|
_WDDQQK(gl)VK_
|
PARP1
|
Ubiquitylation
|
K86
|
1.058
|
|
_VK(gl)KTAEAGGVTGK_
|
PARP1
|
Ubiquitylation
|
K87
|
1.058
|
|
_VK(gl)KTAEAGGVTGK_
|
PARP1
|
Ubiquitylation
|
K97
|
1.386
|
0.406
|
_TAEAGGVTGK(gl)GQDGIGSK_
|
PARP1
|
Ubiquitylation
|
K105
|
0.828
|
|
_GQDGIGSK(gl)AEK_
|
PARP1
|
Ubiquitylation
|
K108
|
1.317
|
|
_GQDGIGSKAEK(gl)_
|
PARP1
|
Ubiquitylation
|
K119
|
1.569
|
|
_TLGDFAAEYAK(gl)SNR_
|
PARP1
|
Ubiquitylation
|
K131
|
1.025
|
1.620
|
_GCMEK(gl)IEK_
|
PARP1
|
Ubiquitylation
|
K197
|
0.445
|
1.157
|
_K(gl)QLPGVK_
|
PARP1
|
Ubiquitylation
|
K254
|
0.589
|
|
_AQNDLIWNIKDELKK(gl)_
|
PARP1
|
Ubiquitylation
|
K262
|
0.456
|
|
_VCSTNDLK(gl)ELLIFNK_
|
PARP1
|
Ubiquitylation
|
K320
|
1.464
|
1.034
|
_SDAYYCTGDVTAWTK(gl)CMVK_
|
PARP1
|
Ubiquitylation
|
K331
|
-0.425
|
-0.480
|
_TQTPNRK(gl)EWVTPK_
|
PARP1
|
Ubiquitylation
|
K337
|
0.462
|
0.332
|
_EWVTPK(gl)EFR_
|
PARP1
|
Ubiquitylation
|
K346
|
0.370
|
0.411
|
_EISYLK(gl)K_
|
PARP1
|
Phosphorylation
|
T368
|
-1.474
|
-1.410
|
_IFPPETSASVAAT(ph)PPPSTASAPAAVNSSASADKPLSNM(ox)K_
|
PARP1
|
Ubiquitylation
|
K400
|
0.844
|
1.095
|
_ILTLGK(gl)LSR_
|
PARP1
|
Ubiquitylation
|
K414
|
1.227
|
1.241
|
_AMIEK(gl)LGGK_
|
PARP1
|
Ubiquitylation
|
K418
|
1.131
|
|
_LGGK(gl)LTGTANK_
|
PARP1
|
Ubiquitylation
|
K425
|
0.912
|
0.815
|
_LTGTANK(gl)ASLCISTKK_
|
PARP1
|
Ubiquitylation
|
K433
|
0.942
|
|
_ASLCISTK(gl)K_
|
PARP1
|
Ubiquitylation
|
K434
|
|
0.020
|
_ASLCISTKK(gl)_
|
PARP1
|
Ubiquitylation
|
K447
|
1.480
|
|
_MEEVK(gl)EANIR_
|
PARP1
|
Ubiquitylation
|
K518
|
0.108
|
|
_GQVKEEGINK(gl)SEK_
|
PARP1
|
Ubiquitylation
|
K521
|
0.630
|
|
_GQVKEEGINKSEK(gl)R_
|
PARP1
|
Ubiquitylation
|
K548
|
0.125
|
-0.480
|
_GGAAVDPDSGLEHSAHVLEK(gl)GGK_
|
PARP1
|
Ubiquitylation
|
K551
|
0.492
|
-0.573
|
_GGAAVDPDSGLEHSAHVLEKGGK(gl)_
|
PARP1
|
Ubiquitylation
|
K629
|
1.632
|
|
_TGNAWHSK(gl)NFTK_
|
PARP1
|
Ubiquitylation
|
K633
|
0.964
|
0.091
|
_NFTK(gl)YPK_
|
PARP1
|
Ubiquitylation
|
K654
|
-0.086
|
|
_K(gl)LTVNPGTK_
|
PARP1
|
Ubiquitylation
|
K662
|
0.112
|
|
_LTVNPGTK(gl)SK_
|
PARP1
|
Ubiquitylation
|
K664
|
-0.042
|
-0.111
|
_LTVNPGTKSK(gl)_
|
PARP1
|
Ubiquitylation
|
K683
|
0.983
|
1.355
|
_MIFDVESM(ox)K(gl)K_
|
PARP1
|
Ubiquitylation
|
K684
|
1.213
|
1.355
|
_MIFDVESMKK(gl)_
|
PARP1
|
Ubiquitylation
|
K700
|
0.448
|
|
_MPLGK(gl)LSK_
|
PARP1
|
Phosphorylation
|
S782
|
0.648
|
0.490
|
_GGS(ph)DDSSKDPIDVNYEK_
|
PARP1
|
Ubiquitylation
|
K949
|
0.738
|
|
_HSVK(gl)GLGK_
|
PNKP
|
Phosphorylation
|
T118
|
-2.016
|
-2.084
|
_TPESQPDT(ph)PPGTPLVSQDEK_
|
PNKP
|
Ubiquitylation
|
K226
|
0.178
|
|
_GK(gl)LPAEEFK_
|
SOX4
|
Phosphorylation
|
S354
|
|
-0.003
|
_SSAASSPAAGRS(ph)PADHR_
|
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