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Query: GLUD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GLUD1 0 -0.160 -0.650 1.550 -0.425 0.134 -1.823 -0.110 0.055
GLUD1 0 -0.160 1.090 -0.240 -0.425 0.134 -1.823 -0.110 0.055

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GLUD1 Ubiquitylation K212 0.459 _FTMELAKK(gl)_
GLUD1 Ubiquitylation K390 -1.159 _QLTK(gl)SNAPR_
GLUD1 Ubiquitylation K191 -1.517 _INPK(gl)NYTDNELEK_

Background Information for GLUD1:


Pubmed-GLUD1 »
Uniprot-GLUD1 »
Biogrid-GLUD1 »
ProteomicsDB-GLUD1 »

Tumorportal-GLUD1 »
COSMIC-GLUD1 »
GenomeRNAi-GLUD1 »
Genecards-GLUD1


Protein-protein Interactions for GLUD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BMPR1A Cat. description Hein, Mann, Cell 2015
Category members IP bait BIRC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLUD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GLUD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glu/Leu/Phe/Val_DH IPR006095 0.31
Category members Glu/Leu/Phe/Val_DH_C IPR006096 0.31
Category members Glu/Leu/Phe/Val_DH_dimer_dom IPR006097 0.31


Protein complexes (CORUM database) featuring GLUD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GLUD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0006541 glutamine metabolic process Database 0.47
Category members GO Category GO:0006538 glutamate catabolic process Database 0.36
Category members GO Category GO:0070728 leucine binding Database 0.36
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0004352 glutamate dehydrogenase (NAD+) activity Database 0.31
Category members GO Category GO:0004353 glutamate dehydrogenase [NAD(P)+] activity Database 0.31
Category members GO Category GO:0043531 ADP binding Database 0.27
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0070403 NAD+ binding Database 0.09
Category members GO Category GO:0032024 positive regulation of insulin secretion Database 0.07
Category members Pathway Pathway_393 KEGG_NITROGEN_METABOLISM 0 0.07
Category members Pathway Pathway_272 KEGG_ALANINE_ASPARTATE_AND_GLUTAMATE_METABOLISM 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_135 KEGG_ARGININE_AND_PROLINE_METABOLISM 0 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_36 KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 0 0
Category members Pathway Pathway_394 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION 0 0
Category members GO Category GO:0006520 cellular amino acid metabolic process Database 0
Category members GO Category GO:0006537 glutamate biosynthetic process Database 0
Category members GO Category GO:0008652 cellular amino acid biosynthetic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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