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REACTOME_GLUCONEOGENESIS
(Pathway_33)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PCK1 3 -0.250 0.020
PCK1 3 -0.250 0.020 -0.618 1.207 -2.619 1.882 1.706
ALDOA 3 -1.420 1.380 0.492 1.786 -1.975 -0.054 -3.073
PCK2 2 0.680 -0.790 -0.618 1.207 -2.619 1.882 1.706
ENO1 1 0.800 -0.580 -0.879 2.255 -2.013 0.739 0.221
PGK1 1 0.880 -0.820 -0.410 0.635 -1.283
PGK2 1 0.450 -0.290 -0.410 0.635 -1.283
GOT2 1 0.300 -0.690
GOT2 1 0.300 -0.690 2.371 -3.377 1.219 0.447
SLC25A13 0 0.700 -0.680 0.224 0.187 0.344
MDH1 0 0.340 -0.770 1.386 0.112
PRKACA 0 0.380 -0.680 -1.005 -0.697 0.234 0.487
GPI 0 0.140 -0.230 -0.881 0.978 0.914
GPI 0 0.140 -0.230
GAPDHS 0 0.660 -0.870 0.283 0.870 0.760 -0.040 -0.473
SLC25A11 0 0.780 -0.330 0.195 0.474 0.294
ALDOC 0 0.860 0.200 -0.960
GAPDH 0 0.130 0.380 0.283 0.870 0.760 -0.040 -0.473
SLC25A12 0 -0.350 0.780 -0.087 0.455 0.279
GOT1 0 -0.320 0.110
PRKACB 0 1.740 -1.200 -1.064
PRKACB 0 1.740 -1.200 -1.005 -0.697 0.234 0.487
PGAM1 0 -0.090 0.080 0.391 0.635
PGAM1 0 0.390 -0.380 0.391 0.635
PGAM2 0 0.890 0.000 0.391 0.635
PGAM4 0 0.391 0.635
PC 0 -0.260 -0.650 -0.229 0.111 0.517
SLC25A10 0 -0.310 0.760 -0.452 -0.345 0.324 0.222
SLC25A10 0 -0.030 0.190 -0.452 -0.345 0.324 0.222
SLC25A10 0 -0.310 0.760 0.553 1.092
SLC25A10 0 -0.030 0.190 0.553 1.092

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ALDOA Ubiquitylation K13 -0.529 _PYQYPALTPEQK(gl)K_
ALDOA Ubiquitylation K14 -0.663 -0.529 _PYQYPALTPEQKK(gl)_
ALDOA Ubiquitylation K28 0.256 0.212 _IVAPGK(gl)GILAADESTGSIAK_
ALDOA Ubiquitylation K42 0.885 1.091 _GILAADESTGSIAK(gl)R_
ALDOA Phosphorylation S46 1.288 1.550 _LQS(ph)IGTENTEENR_
ALDOA Ubiquitylation K99 -0.786 -0.255 _ADDGRPFPQVIK(gl)SK_
ALDOA Ubiquitylation K101 0.994 -0.203 _SK(gl)GGVVGIK_
ALDOA Ubiquitylation K108 0.869 0.736 _SKGGVVGIK(gl)VDK_
ALDOA Ubiquitylation K147 0.764 1.769 _DGADFAK(gl)WR_
ALDOA Ubiquitylation K312 0.854 0.781 _ALQASALK(gl)AWGGK_
ALDOA Ubiquitylation K318 1.490 0.708 _K(gl)ENLK(gl)AAQEEYVKR_
ALDOA Ubiquitylation K322 0.623 0.756 _ENLK(gl)AAQEEYVK(gl)R_
ALDOA Ubiquitylation K330 0.981 1.200 _ENLK(gl)AAQEEYVK(gl)R_
ALDOA Ubiquitylation K342 0.385 _ALANSLACQGK(gl)YTPSGQAGAAASESLFVSNHAY_
ENO1 Ubiquitylation K5 0.389 0.802 _(ac)SILK(gl)IHAR_
ENO1 Ubiquitylation K60 0.769 1.153 _YMGK(gl)GVSK_
ENO1 Ubiquitylation K64 0.708 0.799 _GVSK(gl)AVEHINK_
ENO1 Ubiquitylation K71 0.221 0.294 _AVEHINK(gl)TIAPALVSK_
ENO1 Ubiquitylation K80 0.008 _TIAPALVSK(gl)K_
ENO1 Ubiquitylation K81 0.220 0.476 _K(gl)LNVTEQEKIDK_
ENO1 Ubiquitylation K89 1.139 _KLNVTEQEK(gl)IDK_
ENO1 Ubiquitylation K126 -0.530 0.435 _AGAVEK(gl)GVPLYR_
ENO1 Ubiquitylation K193 1.145 _IGAEVYHNLK(gl)NVIK_
ENO1 Ubiquitylation K197 1.066 1.367 _IGAEVYHNLKNVIK(gl)_
ENO1 Ubiquitylation K199 0.592 0.434 _NVIKEK(gl)YGK_
ENO1 Ubiquitylation K202 -0.137 0.899 _YGK(gl)DATNVGDEGGFAPNILENK_
ENO1 Ubiquitylation K233 0.597 _TAIGK(gl)AGYTDK_
ENO1 Ubiquitylation K256 -0.004 -0.216 _SGK(gl)YDLDFKSPDDPSR_
ENO1 Ubiquitylation K262 -1.294 -0.324 _SGKYDLDFK(gl)SPDDPSR_
ENO1 Phosphorylation S272 0.075 0.358 _YIS(ph)PDQLADLYK_
ENO1 Ubiquitylation K326 -0.383 _FTASAGIQVVGDDLTVTNPK(gl)R_
ENO1 Ubiquitylation K330 1.093 _RIAK(gl)AVNEK_
ENO1 Ubiquitylation K335 0.564 0.437 _AVNEK(gl)SCNCLLLK_
ENO1 Ubiquitylation K406 0.892 0.279 _LAK(gl)YNQLLR_
ENO1 Phosphorylation S419 0.673 0.511 _IEEELGS(ph)KAK_
ENO1 Ubiquitylation K420 0.442 0.409 _IEEELGSK(gl)AK_
ENO1 Ubiquitylation K422 0.439 _IEEELGSKAK(gl)_
ENO1 Ubiquitylation K434 -0.324 _NFRNPLAK(gl)_
GAPDH Ubiquitylation K61 0.521 0.820 _FHGTVK(gl)AENGK_
GAPDH Ubiquitylation K66 -0.023 _FHGTVKAENGK(gl)_
GAPDH Ubiquitylation K86 0.473 _IK(gl)WGDAGAEYVVESTGVFTTMEK_
GAPDH Ubiquitylation K117 1.371 _AGAHLQGGAK(gl)R_
GAPDH Ubiquitylation K145 0.536 0.707 _YDNSLK(gl)IISNASCTTNCLAPLAK_
GAPDH Ubiquitylation K194 0.139 0.426 _TVDGPSGK(gl)LWR_
GAPDH Ubiquitylation K215 0.068 0.425 _GALQNIIPASTGAAK(gl)AVGK_
GAPDH Ubiquitylation K219 0.588 _GALQNIIPASTGAAKAVGK(gl)_
GAPDH Ubiquitylation K254 -0.005 _LEKPAK(gl)YDDIKK_
GAPDH Ubiquitylation K259 -0.052 0.054 _LEKPAKYDDIK(gl)K_
GAPDH Ubiquitylation K260 0.061 -0.269 _LEKPAKYDDIKK(gl)_
GAPDH Ubiquitylation K263 -0.140 0.790 _VVK(gl)QASEGPLK_
GAPDHS Ubiquitylation K61 0.521 0.820 _FHGTVK(gl)AENGK_
GAPDHS Ubiquitylation K66 -0.023 _FHGTVKAENGK(gl)_
GAPDHS Ubiquitylation K86 0.473 _IK(gl)WGDAGAEYVVESTGVFTTMEK_
GAPDHS Ubiquitylation K117 1.371 _AGAHLQGGAK(gl)R_
GAPDHS Ubiquitylation K145 0.536 0.707 _YDNSLK(gl)IISNASCTTNCLAPLAK_
GAPDHS Ubiquitylation K194 0.139 0.426 _TVDGPSGK(gl)LWR_
GAPDHS Ubiquitylation K215 0.068 0.425 _GALQNIIPASTGAAK(gl)AVGK_
GAPDHS Ubiquitylation K219 0.588 _GALQNIIPASTGAAKAVGK(gl)_
GAPDHS Ubiquitylation K254 -0.005 _LEKPAK(gl)YDDIKK_
GAPDHS Ubiquitylation K259 -0.052 0.054 _LEKPAKYDDIK(gl)K_
GAPDHS Ubiquitylation K260 0.061 -0.269 _LEKPAKYDDIKK(gl)_
GAPDHS Ubiquitylation K263 -0.140 0.790 _VVK(gl)QASEGPLK_
GOT1 Ubiquitylation K97 -0.580 _LALGDDSPALK(gl)EK_
GOT2 Ubiquitylation K321 -1.209 _TQLVSNLKK(gl)_
GPI Ubiquitylation K12 0.115 0.544 _DPQFQK(gl)LQQWYR_
GPI Ubiquitylation K73 0.646 1.187 _MLVDLAK(gl)SR_
GPI Ubiquitylation K89 -0.366 1.232 _MFNGEK(gl)INYTEGR_
GPI Phosphorylation S107 -0.341 0.159 _S(ph)NTPILVDGKDVM(ox)PEVNK_
GPI Phosphorylation T109 0.024 -0.027 _SNT(ph)PILVDGK_
GPI Ubiquitylation K116 0.504 _SNTPILVDGK(gl)DVMPEVNK_
GPI Ubiquitylation K130 0.931 1.163 _MK(gl)SFCQR_
GPI Ubiquitylation K142 0.922 1.123 _SGDWK(gl)GYTGK_
GPI Ubiquitylation K234 -0.228 0.467 _EWFLQAAK(gl)DPSAVAK_
GPI Ubiquitylation K241 0.187 0.264 _DPSAVAK(gl)HFVALSTNTTK_
GPI Ubiquitylation K362 0.882 _FAAYFQQGDMESNGK(gl)YITK_
GPI Ubiquitylation K366 0.484 0.754 _YITK(gl)SGTR_
GPI Ubiquitylation K447 0.643 0.199 _STEEARK(gl)ELQAAGK_
GPI Ubiquitylation K454 -0.613 -0.505 _ELQAAGK(gl)SPEDLER_
MDH1 Ubiquitylation K121 1.157 0.308 _DLLK(gl)ANVK_
MDH1 Ubiquitylation K160 -1.596 _VIVVGNPANTNCLTASK(gl)SAPSIPK_
MDH1 Ubiquitylation K232 -0.046 _EVGVYEALK(gl)DDSWLK_
MDH1 Ubiquitylation K238 -0.272 _EVGVYEALK(gl)DDSWLK_
MDH1 Ubiquitylation K254 -0.543 _GAAVIK(gl)AR_
MDH1 Ubiquitylation K330 0.073 _EK(gl)MDLTAK_
PCK1 Phosphorylation S13 1.866 0.458 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1 Phosphorylation S19 1.866 -1.827 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1 Phosphorylation S22 1.866 0.458 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PGAM1 Ubiquitylation K5 0.678 0.409 _AAYK(gl)LVLIR_
PGAM1 Phosphorylation S31 -0.052 _FSGWYDADLS(ph)PAGHEEAK_
PGAM1 Ubiquitylation K100 0.587 _HYGGLTGLNK(gl)AETAAK_
PGAM1 Ubiquitylation K106 0.730 0.582 _AETAAK(gl)HGEAQVK_
PGAM1 Ubiquitylation K113 0.879 _HGEAQVK(gl)IWR_
PGAM1 Phosphorylation S118 -1.405 -1.243 _S(ph)YDVPPPPMEPDHPFYSNISK_
PGAM1 Ubiquitylation K157 -0.481 _YADLTEDQLPSCESLK(gl)DTIAR_
PGAM1 Ubiquitylation K241 1.095 _K(gl)AMEAVAAQGK_
PGAM1 Ubiquitylation K251 0.496 0.796 _KAMEAVAAQGK(gl)AK_
PGAM1 Ubiquitylation K253 0.862 0.716 _AMEAVAAQGKAK(gl)_
PGAM2 Ubiquitylation K5 0.678 0.409 _AAYK(gl)LVLIR_
PGAM2 Phosphorylation S31 -0.052 _FSGWYDADLS(ph)PAGHEEAK_
PGAM2 Ubiquitylation K100 0.587 _HYGGLTGLNK(gl)AETAAK_
PGAM2 Ubiquitylation K106 0.730 0.582 _AETAAK(gl)HGEAQVK_
PGAM2 Ubiquitylation K113 0.879 _HGEAQVK(gl)IWR_
PGAM2 Phosphorylation S118 -1.405 -1.243 _S(ph)YDVPPPPMEPDHPFYSNISK_
PGAM2 Ubiquitylation K157 -0.481 _YADLTEDQLPSCESLK(gl)DTIAR_
PGAM2 Ubiquitylation K241 1.095 _K(gl)AMEAVAAQGK_
PGAM2 Ubiquitylation K251 0.496 0.796 _KAMEAVAAQGK(gl)AK_
PGAM2 Ubiquitylation K253 0.862 0.716 _AMEAVAAQGKAK(gl)_
PGAM4 Ubiquitylation K5 0.678 0.409 _AAYK(gl)LVLIR_
PGAM4 Phosphorylation S31 -0.052 _FSGWYDADLS(ph)PAGHEEAK_
PGAM4 Ubiquitylation K100 0.587 _HYGGLTGLNK(gl)AETAAK_
PGAM4 Ubiquitylation K106 0.730 0.582 _AETAAK(gl)HGEAQVK_
PGAM4 Ubiquitylation K113 0.879 _HGEAQVK(gl)IWR_
PGAM4 Phosphorylation S118 -1.405 -1.243 _S(ph)YDVPPPPMEPDHPFYSNISK_
PGAM4 Ubiquitylation K157 -0.481 _YADLTEDQLPSCESLK(gl)DTIAR_
PGAM4 Ubiquitylation K241 1.095 _K(gl)AMEAVAAQGK_
PGAM4 Ubiquitylation K251 0.496 0.796 _KAMEAVAAQGK(gl)AK_
PGAM4 Ubiquitylation K253 0.862 0.716 _AMEAVAAQGKAK(gl)_
PGK1 Ubiquitylation K6 0.130 0.442 _(ac)SLSNK(gl)LTLDKLDVK_
PGK1 Ubiquitylation K15 0.699 0.424 _LTLDKLDVK(gl)GK_
PGK1 Ubiquitylation K17 0.456 _LTLDKLDVKGK(gl)_
PGK1 Ubiquitylation K30 0.451 0.136 _VDFNVPM(ox)K(gl)NNQITNNQR_
PGK1 Ubiquitylation K41 0.735 0.921 _IK(gl)AAVPSIK_
PGK1 Ubiquitylation K97 0.101 _DVLFLK(gl)DCVGPEVEK_
PGK1 Ubiquitylation K141 0.899 -0.415 _VK(gl)AEPAKIEAFR_
PGK1 Ubiquitylation K146 0.183 _AEPAK(gl)IEAFR_
PGK1 Ubiquitylation K191 0.890 _AGGFLMK(gl)K_
PGK1 Ubiquitylation K192 0.222 _K(gl)ELNYFAK_
PGK1 Phosphorylation S203 0.126 0.077 _ALES(ph)PERPFLAILGGAK_
PGK1 Ubiquitylation K267 1.728 1.011 _IVK(gl)DLMSK_
PGK1 Ubiquitylation K272 1.427 _DLMSK(gl)AEK_
PGK1 Ubiquitylation K322 -0.414 _TGQATVASGIPAGWMGLDCGPESSK(gl)K_
PGK1 Ubiquitylation K323 -0.064 -0.414 _TGQATVASGIPAGWMGLDCGPESSKK(gl)_
PGK1 Ubiquitylation K353 0.918 _GTK(gl)ALMDEVVK_
PGK1 Ubiquitylation K361 0.663 0.384 _ALMDEVVK(gl)ATSR_
PGK2 Ubiquitylation K6 0.130 0.442 _(ac)SLSNK(gl)LTLDKLDVK_
PGK2 Ubiquitylation K15 0.699 0.424 _LTLDKLDVK(gl)GK_
PGK2 Ubiquitylation K17 0.456 _LTLDKLDVKGK(gl)_
PGK2 Ubiquitylation K30 0.451 0.136 _VDFNVPM(ox)K(gl)NNQITNNQR_
PGK2 Ubiquitylation K41 0.735 0.921 _IK(gl)AAVPSIK_
PGK2 Ubiquitylation K97 0.101 _DVLFLK(gl)DCVGPEVEK_
PGK2 Ubiquitylation K141 0.899 -0.415 _VK(gl)AEPAKIEAFR_
PGK2 Ubiquitylation K146 0.183 _AEPAK(gl)IEAFR_
PGK2 Ubiquitylation K191 0.890 _AGGFLMK(gl)K_
PGK2 Ubiquitylation K192 0.222 _K(gl)ELNYFAK_
PGK2 Phosphorylation S203 0.126 0.077 _ALES(ph)PERPFLAILGGAK_
PGK2 Ubiquitylation K267 1.728 1.011 _IVK(gl)DLMSK_
PGK2 Ubiquitylation K272 1.427 _DLMSK(gl)AEK_
PGK2 Ubiquitylation K322 -0.414 _TGQATVASGIPAGWMGLDCGPESSK(gl)K_
PGK2 Ubiquitylation K323 -0.064 -0.414 _TGQATVASGIPAGWMGLDCGPESSKK(gl)_
PGK2 Ubiquitylation K353 0.918 _GTK(gl)ALMDEVVK_
PGK2 Ubiquitylation K361 0.663 0.384 _ALMDEVVK(gl)ATSR_
PRKACA Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACA Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Ubiquitylation K30 -0.143 _AKEDFLKK(gl)_
PRKACB Ubiquitylation K93 0.839 0.714 _QIEHTLNEK(gl)R_
PRKACB Phosphorylation T243 -0.835 _T(ph)WTLCGTPEYLAPEIILSK_
PRKACB Phosphorylation T245 -0.116 -0.102 _TWT(ph)LCGTPEYLAPEIILSK_
SLC25A11 Ubiquitylation K15 -0.855 0.190 _(ac)AATASAGAGGIDGK(gl)PR_
SLC25A11 Ubiquitylation K57 0.010 _MQLSGEGAK(gl)TR_
SLC25A13 Ubiquitylation K5 0.019 _(ac)AAAK(gl)VALTK_


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