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Query: PGAM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PGAM1 0 1.460 -0.090 0.080 0.391 0.635
PGAM1 0 1.460 0.390 -0.380 0.391 0.635

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PGAM1 Ubiquitylation K251 0.496 0.796 _KAMEAVAAQGK(gl)AK_
PGAM1 Ubiquitylation K253 0.862 0.716 _AMEAVAAQGKAK(gl)_
PGAM1 Ubiquitylation K106 0.730 0.582 _AETAAK(gl)HGEAQVK_
PGAM1 Ubiquitylation K5 0.678 0.409 _AAYK(gl)LVLIR_
PGAM1 Phosphorylation S31 -0.052 _FSGWYDADLS(ph)PAGHEEAK_
PGAM1 Phosphorylation S118 -1.405 -1.243 _S(ph)YDVPPPPMEPDHPFYSNISK_
PGAM1 Ubiquitylation K100 0.587 _HYGGLTGLNK(gl)AETAAK_
PGAM1 Ubiquitylation K113 0.879 _HGEAQVK(gl)IWR_
PGAM1 Ubiquitylation K157 -0.481 _YADLTEDQLPSCESLK(gl)DTIAR_
PGAM1 Ubiquitylation K241 1.095 _K(gl)AMEAVAAQGK_

Background Information for PGAM1:


Pubmed-PGAM1 »
Uniprot-PGAM1 »
Biogrid-PGAM1 »
ProteomicsDB-PGAM1 »

Tumorportal-PGAM1 »
COSMIC-PGAM1 »
GenomeRNAi-PGAM1 »
Genecards-PGAM1


Protein-protein Interactions for PGAM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PGAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PGAM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Phosphogly_mut1 IPR005952 0.04
Category members His_Pase_superF_clade-1 IPR013078 0
Category members His_PPase_superfam IPR029033 0


Protein complexes (CORUM database) featuring PGAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PGAM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_57 REACTOME_GLYCOLYSIS 0 4.41
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_59 BIOCARTA_GLYCOLYSIS_PATHWAY 0 1.96
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members Pathway Pathway_33 REACTOME_GLUCONEOGENESIS 0 1.41
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0004082 bisphosphoglycerate mutase activity Database 0
Category members GO Category GO:0004083 bisphosphoglycerate 2-phosphatase activity Database 0
Category members GO Category GO:0004619 phosphoglycerate mutase activity Database 0
Category members GO Category GO:0006110 regulation of glycolysis Database 0
Category members GO Category GO:0016868 intramolecular transferase activity, phosphotransferases Database 0
Category members GO Category GO:0045730 respiratory burst Database 0


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