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Query: ENO1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ENO1 1 4.013 0.800 -0.580 -0.879 2.255 -2.013 0.739 0.221

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ENO1 Ubiquitylation K197 1.066 1.367 _IGAEVYHNLKNVIK(gl)_
ENO1 Ubiquitylation K60 0.769 1.153 _YMGK(gl)GVSK_
ENO1 Ubiquitylation K193 1.145 _IGAEVYHNLK(gl)NVIK_
ENO1 Ubiquitylation K202 -0.137 0.899 _YGK(gl)DATNVGDEGGFAPNILENK_
ENO1 Ubiquitylation K5 0.389 0.802 _(ac)SILK(gl)IHAR_
ENO1 Ubiquitylation K64 0.708 0.799 _GVSK(gl)AVEHINK_
ENO1 Phosphorylation S419 0.673 0.511 _IEEELGS(ph)KAK_
ENO1 Ubiquitylation K81 0.220 0.476 _K(gl)LNVTEQEKIDK_
ENO1 Ubiquitylation K422 0.439 _IEEELGSKAK(gl)_
ENO1 Ubiquitylation K335 0.564 0.437 _AVNEK(gl)SCNCLLLK_
ENO1 Ubiquitylation K126 -0.530 0.435 _AGAVEK(gl)GVPLYR_
ENO1 Ubiquitylation K199 0.592 0.434 _NVIKEK(gl)YGK_
ENO1 Ubiquitylation K420 0.442 0.409 _IEEELGSK(gl)AK_
ENO1 Phosphorylation S272 0.075 0.358 _YIS(ph)PDQLADLYK_
ENO1 Ubiquitylation K71 0.221 0.294 _AVEHINK(gl)TIAPALVSK_
ENO1 Ubiquitylation K406 0.892 0.279 _LAK(gl)YNQLLR_
ENO1 Ubiquitylation K256 -0.004 -0.216 _SGK(gl)YDLDFKSPDDPSR_
ENO1 Ubiquitylation K262 -1.294 -0.324 _SGKYDLDFK(gl)SPDDPSR_
ENO1 Ubiquitylation K434 -0.324 _NFRNPLAK(gl)_
ENO1 Ubiquitylation K80 0.008 _TIAPALVSK(gl)K_
ENO1 Ubiquitylation K89 1.139 _KLNVTEQEK(gl)IDK_
ENO1 Ubiquitylation K233 0.597 _TAIGK(gl)AGYTDK_
ENO1 Ubiquitylation K326 -0.383 _FTASAGIQVVGDDLTVTNPK(gl)R_
ENO1 Ubiquitylation K330 1.093 _RIAK(gl)AVNEK_

Background Information for ENO1:


Pubmed-ENO1 »
Uniprot-ENO1 »
Biogrid-ENO1 »
ProteomicsDB-ENO1 »

Tumorportal-ENO1 »
COSMIC-ENO1 »
GenomeRNAi-ENO1 »
Genecards-ENO1


Protein-protein Interactions for ENO1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ATP6AP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZBTB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait ENO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ENO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ENO1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Enolase IPR000941 0
Category members Enolase_C IPR020810 0
Category members Enolase_N IPR020811 0
Category members Enolase_N_like IPR029017 0
Category members Enolase_C-like IPR029065 0


Protein complexes (CORUM database) featuring ENO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ENO1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_57 REACTOME_GLYCOLYSIS 0 4.41
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_59 BIOCARTA_GLYCOLYSIS_PATHWAY 0 1.96
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members Pathway Pathway_33 REACTOME_GLUCONEOGENESIS 0 1.41
Category members GO Category GO:0070062 extracellular vesicular exosome Database 1.36
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members Pathway Pathway_849 PID_NOTCH_PATHWAY 0 0.29
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members Pathway Pathway_52 PID_HIF1_TFPATHWAY 0 0.11
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0000015 phosphopyruvate hydratase complex Database 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0004634 phosphopyruvate hydratase activity Database 0
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0031430 M band Database 0


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