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Query: GAPDHS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GAPDHS 0 2.721 0.660 -0.870 0.283 0.870 0.760 -0.040 -0.473

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GAPDHS Ubiquitylation K61 0.521 0.820 _FHGTVK(gl)AENGK_
GAPDHS Ubiquitylation K263 -0.140 0.790 _VVK(gl)QASEGPLK_
GAPDHS Ubiquitylation K145 0.536 0.707 _YDNSLK(gl)IISNASCTTNCLAPLAK_
GAPDHS Ubiquitylation K219 0.588 _GALQNIIPASTGAAKAVGK(gl)_
GAPDHS Ubiquitylation K194 0.139 0.426 _TVDGPSGK(gl)LWR_
GAPDHS Ubiquitylation K215 0.068 0.425 _GALQNIIPASTGAAK(gl)AVGK_
GAPDHS Ubiquitylation K259 -0.052 0.054 _LEKPAKYDDIK(gl)K_
GAPDHS Ubiquitylation K260 0.061 -0.269 _LEKPAKYDDIKK(gl)_
GAPDHS Ubiquitylation K66 -0.023 _FHGTVKAENGK(gl)_
GAPDHS Ubiquitylation K86 0.473 _IK(gl)WGDAGAEYVVESTGVFTTMEK_
GAPDHS Ubiquitylation K117 1.371 _AGAHLQGGAK(gl)R_
GAPDHS Ubiquitylation K254 -0.005 _LEKPAK(gl)YDDIKK_

Background Information for GAPDHS:





Protein-protein Interactions for GAPDHS

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADCK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BATF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf93 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C12orf50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C16orf73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf39 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DARS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM117B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GALNTL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GDE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPX8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HYAL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ITK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KCNA10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLRF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LINGO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAFF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MFSD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MGST3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NCAPD3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUSAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ODF2L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHACTR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSG11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTPN20A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASGEF1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SAMD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC39A11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC5A2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM220 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRA2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIP6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZDHHC23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF684 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GAPDHS

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glyceraldehyde-3-P_DH_1 IPR006424 0
Category members GlycerAld_3-P_DH_NAD(P)-bd IPR020828 0
Category members GlycerAld_3-P_DH_cat IPR020829 0
Category members GlycerAld/Erythrose_P_DH IPR020831 0


Protein complexes (CORUM database) featuring GAPDHS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GAPDHS

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_57 REACTOME_GLYCOLYSIS 0 4.41
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members Pathway Pathway_33 REACTOME_GLUCONEOGENESIS 0 1.41
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members GO Category GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor Database 0
Category members GO Category GO:0030317 sperm motility Database 0
Category members GO Category GO:0031514 motile cilium Database 0
Category members GO Category GO:0045821 positive regulation of glycolysis Database 0
Category members GO Category GO:0050661 NADP binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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