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Query: PCK1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PCK1 3 3.902 -0.250 0.020
PCK1 3 3.902 -0.250 0.020 -0.618 1.207 -2.619 1.882 1.706

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PCK1 Phosphorylation S13 1.866 0.458 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1 Phosphorylation S22 1.866 0.458 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_
PCK1 Phosphorylation S19 1.866 -1.827 _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_

Background Information for PCK1:


Pubmed-PCK1 »
Uniprot-PCK1 »
Biogrid-PCK1 »
ProteomicsDB-PCK1 »

Tumorportal-PCK1 »
COSMIC-PCK1 »
GenomeRNAi-PCK1 »
Genecards-PCK1


Protein-protein Interactions for PCK1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PCK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PCK1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PEP_carboxykinase_GTP IPR008209 0.09
Category members PEP_carboxykinase_N IPR008210 0.09


Protein complexes (CORUM database) featuring PCK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PCK1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members Pathway Pathway_35 REACTOME_GLUCOSE_METABOLISM 0 1.79
Category members GO Category GO:0006094 gluconeogenesis Database 1.42
Category members Pathway Pathway_33 REACTOME_GLUCONEOGENESIS 0 1.41
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members GO Category GO:0006475 internal protein amino acid acetylation Database 0.35
Category members Pathway Pathway_41 REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION 0 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_42 REACTOME_DEVELOPMENTAL_BIOLOGY 0 0.32
Category members Pathway Pathway_34 REACTOME_METABOLISM_OF_CARBOHYDRATES 0 0.31
Category members GO Category GO:0006006 glucose metabolic process Database 0.28
Category members GO Category GO:0016301 kinase activity Database 0.23
Category members GO Category GO:0017076 purine nucleotide binding Database 0.23
Category members Pathway Pathway_44 KEGG_INSULIN_SIGNALING_PATHWAY 0 0.21
Category members GO Category GO:0019003 GDP binding Database 0.18
Category members GO Category GO:0042593 glucose homeostasis Database 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0004611 phosphoenolpyruvate carboxykinase activity Database 0.09
Category members GO Category GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity Database 0.09
Category members Pathway Pathway_38 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM 0 0.08
Category members Pathway Pathway_39 PID_HNF3B_PATHWAY 0 0.08
Category members GO Category GO:0005975 carbohydrate metabolic process Database 0.07
Category members Pathway Pathway_36 KEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION 0 0
Category members Pathway Pathway_40 KEGG_ADIPOCYTOKINE_SIGNALING_PATHWAY 0 0
Category members Pathway Pathway_43 KEGG_PPAR_SIGNALING_PATHWAY 0 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0006107 oxaloacetate metabolic process Database 0
Category members GO Category GO:0006629 lipid metabolic process Database 0
Category members GO Category GO:0014823 response to activity Database 0
Category members GO Category GO:0017144 drug metabolic process Database 0
Category members GO Category GO:0030145 manganese ion binding Database 0
Category members GO Category GO:0031406 carboxylic acid binding Database 0
Category members GO Category GO:0032868 response to insulin Database 0


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