Results for the Category
KEGG_CITRATE_CYCLE_TCA_CYCLE
(Pathway_3)
| RNAi screen result | RNAPII IP (MG132) | CSB IP | CSB IP (MG132) | Chrom. | Chrom. (MG132) | Ubi /Phospo | Ubi /Phospho (MG132) |
| W | |||||||
| Gene name | MGoogle Score | RNAi high | RNAi low | RNAPII-IP (MG132) | CSB-IP | CSB-IP (MG132) | Chrom. | Chrom. (MG132) |
|---|---|---|---|---|---|---|---|---|
| PCK1 | 3 | -0.250 | 0.020 | |||||
| PCK1 | 3 | -0.250 | 0.020 | -0.618 | 1.207 | -2.619 | 1.882 | 1.706 |
| PCK2 | 2 | 0.680 | -0.790 | -0.618 | 1.207 | -2.619 | 1.882 | 1.706 |
| SUCLA2 | 2 | -2.060 | 3.390 | -0.138 | 1.977 | 1.093 | 0.543 | |
| CS | 1 | 1.370 | -0.830 | 0.982 | 1.925 | -2.498 | 0.510 | 0.426 |
| ACO2 | 1 | 0.840 | -0.860 | 0.064 | 1.695 | -0.763 | 1.166 | 0.817 |
| OGDH | 1 | -1.280 | 1.690 | 2.037 | 0.608 | -0.247 | -0.806 | 0.482 |
| DLST | 1 | 0.420 | -0.640 | 2.196 | 0.288 | -0.284 | 0.902 | 0.581 |
| ACO1 | 1 | -2.080 | 4.040 | |||||
| ACLY | 1 | 1.120 | -0.800 | |||||
| PDHA1 | 1 | -0.760 | 1.860 | |||||
| PDHA1 | 1 | 0.410 | -0.200 | |||||
| PDHA1 | 1 | -0.760 | 1.860 | 0.830 | -0.675 | -1.114 | 0.710 | 0.474 |
| PDHA1 | 1 | 0.410 | -0.200 | 0.830 | -0.675 | -1.114 | 0.710 | 0.474 |
| IDH1 | 1 | 0.390 | -0.320 | 1.581 | 0.783 | |||
| PDHA2 | 1 | 1.440 | -0.270 | |||||
| PDHA2 | 1 | 1.440 | -0.270 | 3.944 | ||||
| IDH2 | 1 | 0.090 | -0.520 | 0.923 | -2.210 | 2.164 | 1.203 | |
| OGDHL | 1 | 2.037 | 0.608 | -0.247 | -0.806 | 0.482 | ||
| MDH1 | 0 | 0.340 | -0.770 | 1.386 | 0.112 | |||
| SDHA | 0 | 1.350 | -1.030 | 0.223 | 0.787 | 0.745 | ||
| SDHA | 0 | 1.350 | -1.030 | 0.602 | 0.333 | -0.951 | 0.718 | 0.496 |
| DLD | 0 | -0.420 | 0.270 | 1.380 | 0.780 | -1.052 | 0.824 | 0.231 |
| FH | 0 | 1.300 | -0.210 | 1.313 | 0.652 | |||
| IDH3B | 0 | 0.600 | 0.900 | 1.060 | 1.064 | -0.360 | 0.606 | 0.386 |
| SDHB | 0 | -0.720 | 0.810 | -0.156 | -0.332 | -1.201 | 0.467 | 0.434 |
| SDHC | 0 | 0.700 | -0.920 | 0.734 | ||||
| SUCLG1 | 0 | 1.830 | -0.660 | -0.333 | 0.820 | -0.251 | ||
| IDH3A | 0 | 0.580 | -0.500 | 0.488 | 1.195 | -0.834 | 0.675 | 0.445 |
| PDHB | 0 | 0.900 | -0.430 | 0.391 | -0.584 | -1.115 | 0.816 | 0.253 |
| SUCLG2 | 0 | 0.340 | 0.190 | 0.944 | 0.581 | 0.438 | ||
| SUCLG2 | 0 | 1.390 | -0.440 | 0.944 | 0.581 | 0.438 | ||
| PC | 0 | -0.260 | -0.650 | -0.229 | 0.111 | 0.517 |
| Gene name | PTM type | PTM site | UV | UV (MG132) | Sequence |
|---|---|---|---|---|---|
| ACLY | Ubiquitylation | K210 | -0.990 | _AK(gl)PAMPQGK_ | |
| ACLY | Ubiquitylation | K217 | -0.283 | -0.673 | _AKPAM(ox)PQGK(gl)STTLFSR_ |
| ACO1 | Ubiquitylation | K79 | -0.349 | _NIEVPFK(gl)PAR_ | |
| ACO1 | Ubiquitylation | K396 | -0.346 | _DFESCLGAK(gl)QGFK_ | |
| ACO2 | Ubiquitylation | K13 | -1.183 | _LQK(gl)ALGVR_ | |
| CS | Ubiquitylation | K103 | -0.259 | 0.372 | _GFSIPECQK(gl)LLPK_ |
| CS | Ubiquitylation | K107 | -0.496 | _GFSIPECQKLLPK(gl)_ | |
| CS | Ubiquitylation | K215 | -0.426 | -0.352 | _LPCVAAK(gl)IYR_ |
| IDH1 | Ubiquitylation | K58 | -0.442 | 0.097 | _DATNDQVTK(gl)DAAEAIKK_ |
| IDH3A | Ubiquitylation | K177 | -0.835 | _LITEGASK(gl)R_ | |
| IDH3A | Ubiquitylation | K200 | -1.507 | _SNVTAVHK(gl)ANIMR_ | |
| IDH3A | Ubiquitylation | K214 | -0.957 | _MSDGLFLQK(gl)CR_ | |
| IDH3A | Ubiquitylation | K336 | -0.022 | -0.342 | _IEAACFATIK(gl)DGK_ |
| IDH3A | Ubiquitylation | K343 | -0.549 | _SLTK(gl)DLGGNAK_ | |
| MDH1 | Ubiquitylation | K121 | 1.157 | 0.308 | _DLLK(gl)ANVK_ |
| MDH1 | Ubiquitylation | K160 | -1.596 | _VIVVGNPANTNCLTASK(gl)SAPSIPK_ | |
| MDH1 | Ubiquitylation | K232 | -0.046 | _EVGVYEALK(gl)DDSWLK_ | |
| MDH1 | Ubiquitylation | K238 | -0.272 | _EVGVYEALK(gl)DDSWLK_ | |
| MDH1 | Ubiquitylation | K254 | -0.543 | _GAAVIK(gl)AR_ | |
| MDH1 | Ubiquitylation | K330 | 0.073 | _EK(gl)MDLTAK_ | |
| PCK1 | Phosphorylation | S13 | 1.866 | 0.458 | _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_ |
| PCK1 | Phosphorylation | S19 | 1.866 | -1.827 | _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_ |
| PCK1 | Phosphorylation | S22 | 1.866 | 0.458 | _(ac)TTGRTM(ox)YVIPFS(ph)M(ox)GPLGS(ph)PLS(ph)K_ |
| PDHA1 | Phosphorylation | T231 | 1.539 | 1.081 | _YGMGT(ph)SVER_ |
| PDHA1 | Phosphorylation | S232 | 1.452 | 0.823 | _YGM(ox)GTS(ph)VER_ |
| PDHA1 | Ubiquitylation | K244 | -0.931 | _AAASTDYYK(gl)R_ | |
| PDHA1 | Phosphorylation | S293 | 0.346 | 0.996 | _YHGHS(ph)M(ox)SDPGVSYR_ |
| PDHA1 | Phosphorylation | S295 | 0.274 | 0.755 | _YHGHSMS(ph)DPGVSYR_ |
| PDHA2 | Phosphorylation | S293 | 0.346 | 0.996 | _YHGHS(ph)M(ox)SDPGVSYR_ |
| PDHA2 | Phosphorylation | S295 | 0.274 | 0.755 | _YHGHSMS(ph)DPGVSYR_ |
| PDHB | Ubiquitylation | K229 | -1.242 | _DFLIPIGKAK(gl)_ | |
| SDHA | Ubiquitylation | K341 | -1.790 | _YAPVAK(gl)DLASR_ |
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