bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: SDHC

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SDHC 0 0.734 0.700 -0.920 0.734

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SDHC:


Pubmed-SDHC »
Uniprot-SDHC »
Biogrid-SDHC »
ProteomicsDB-SDHC »

Tumorportal-SDHC »
COSMIC-SDHC »
GenomeRNAi-SDHC »
Genecards-SDHC


Protein-protein Interactions for SDHC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IMPDH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SDHC
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring SDHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SDHC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_50 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ 0 0.7
Category members Pathway Pathway_32 KEGG_HUNTINGTONS_DISEASE 0 0.46
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Disease phenotype Gastrointestinal_stromal_tumor Gastrointestinal stromal tumor Database 0.22
Category members Pathway Pathway_49 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT 0 0.17
Category members GO Category GO:0022904 respiratory electron transport chain Database 0.15
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0009060 aerobic respiration Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0020037 heme binding Database 0.04
Category members Disease phenotype COWDEN_SYNDROME COWDEN SYNDROME Database 0.03
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Pathway Pathway_29 KEGG_ALZHEIMERS_DISEASE 0 0
Category members Pathway Pathway_30 KEGG_OXIDATIVE_PHOSPHORYLATION 0 0
Category members Pathway Pathway_31 KEGG_PARKINSONS_DISEASE 0 0
Category members Pathway Pathway_48 BIOCARTA_ETC_PATHWAY 0 0
Category members Disease phenotype Carney-Stratakis_syndrome Carney-Stratakis syndrome Database 0
Category members Disease phenotype Hereditary_pheochromocytoma-paraganglioma Hereditary pheochromocytoma-paraganglioma Database 0
Category members Disease phenotype PARAGANGLIOMA_AND_GASTRIC_STROMAL_SARCOMA PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA Database 0
Category members GO Category GO:0000104 succinate dehydrogenase activity Database 0
Category members GO Category GO:0005749 mitochondrial respiratory chain complex II Database 0
Category members GO Category GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


.

© Copyright Svejstrup Laboratory 2015