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Query: OGDH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
OGDH 1 4.011 -1.280 1.690 2.037 0.608 -0.247 -0.806 0.482

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for OGDH:


Pubmed-OGDH »
Uniprot-OGDH »
Biogrid-OGDH »
ProteomicsDB-OGDH »

Tumorportal-OGDH »
COSMIC-OGDH »
GenomeRNAi-OGDH »
Genecards-OGDH


Protein-protein Interactions for OGDH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CAPZA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC5 Cat. description Hein, Mann, Cell 2015
Category members IP bait HDAC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait DLD Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in OGDH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_E1 IPR001017 0.19
Category members THDP-binding IPR029061 0.04
Category members Transketolase-like_Pyr-bd IPR005475 0.01
Category members 2oxoglutarate_DH_E1 IPR011603 0


Protein complexes (CORUM database) featuring OGDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring OGDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0051087 chaperone binding Database 1.69
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members Pathway Pathway_8 BIOCARTA_KREB_PATHWAY 0 1.35
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0006104 succinyl-CoA metabolic process Database 0.68
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0045252 oxoglutarate dehydrogenase complex Database 0.28
Category members GO Category GO:0006734 NADH metabolic process Database 0.26
Category members GO Category GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Database 0.19
Category members GO Category GO:0021860 pyramidal neuron development Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_37 KEGG_TRYPTOPHAN_METABOLISM 0 0.06
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members GO Category GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity Database 0
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0006103 2-oxoglutarate metabolic process Database 0
Category members GO Category GO:0006554 lysine catabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0021695 cerebellar cortex development Database 0
Category members GO Category GO:0021756 striatum development Database 0
Category members GO Category GO:0021766 hippocampus development Database 0
Category members GO Category GO:0021794 thalamus development Database 0
Category members GO Category GO:0022028 tangential migration from the subventricular zone to the olfactory bulb Database 0
Category members GO Category GO:0030976 thiamine pyrophosphate binding Database 0
Category members GO Category GO:0031966 mitochondrial membrane Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0
Category members GO Category GO:0061034 olfactory bulb mitral cell layer development Database 0


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