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Query: SUCLA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SUCLA2 2 6.865 -2.060 3.390 -0.138 1.977 1.093 0.543

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for SUCLA2:


Pubmed-SUCLA2 »
Uniprot-SUCLA2 »
Biogrid-SUCLA2 »
ProteomicsDB-SUCLA2 »

Tumorportal-SUCLA2 »
COSMIC-SUCLA2 »
GenomeRNAi-SUCLA2 »
Genecards-SUCLA2


Protein-protein Interactions for SUCLA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SUCLA2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUCLG1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SUCLA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CoA_ligase IPR005811 0.35
Category members Succinyl-CoA_synth-like IPR016102 0.35
Category members Succ_CoA_synthase_bsu IPR005809 0.31
Category members ATP-grasp_succ-CoA_synth-type IPR013650 0.31


Protein complexes (CORUM database) featuring SUCLA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 394 Succinyl-CoA synthetase, ADP-forming Database 0.13


Categories featuring SUCLA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_28 KEGG_PROPANOATE_METABOLISM 0 1.89
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_8 BIOCARTA_KREB_PATHWAY 0 1.35
Category members GO Category GO:0006104 succinyl-CoA metabolic process Database 0.68
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0004775 succinate-CoA ligase (ADP-forming) activity Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006105 succinate metabolic process Database 0.31
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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