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Query: PDHA2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PDHA2 1 5.286 1.440 -0.270
PDHA2 1 5.286 1.440 -0.270 3.944

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PDHA2 Phosphorylation S293 0.346 0.996 _YHGHS(ph)M(ox)SDPGVSYR_
PDHA2 Phosphorylation S295 0.274 0.755 _YHGHSMS(ph)DPGVSYR_

Background Information for PDHA2:


Pubmed-PDHA2 »
Uniprot-PDHA2 »
Biogrid-PDHA2 »
ProteomicsDB-PDHA2 »

Tumorportal-PDHA2 »
COSMIC-PDHA2 »
GenomeRNAi-PDHA2 »
Genecards-PDHA2


Protein-protein Interactions for PDHA2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait APBA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PDHA2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DH_E1 IPR001017 0.19
Category members Pyrv_DH_E1_asu_subgrp-y IPR017597 0.09
Category members THDP-binding IPR029061 0.04


Protein complexes (CORUM database) featuring PDHA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PDHA2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members GO Category GO:0006096 glycolysis Database 2.49
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_16 KEGG_PYRUVATE_METABOLISM 0 1.34
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor Database 0.19
Category members Pathway Pathway_47 KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_BIOSYNTHESIS 0 0.09
Category members GO Category GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity Database 0.07
Category members GO Category GO:0006090 pyruvate metabolic process Database 0.04
Category members Pathway Pathway_46 KEGG_BUTANOATE_METABOLISM 0 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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