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Query: ACO2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ACO2 1 1.796 0.840 -0.860 0.064 1.695 -0.763 1.166 0.817

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ACO2 Ubiquitylation K13 -1.183 _LQK(gl)ALGVR_

Background Information for ACO2:


Pubmed-ACO2 »
Uniprot-ACO2 »
Biogrid-ACO2 »
ProteomicsDB-ACO2 »

Tumorportal-ACO2 »
COSMIC-ACO2 »
GenomeRNAi-ACO2 »
Genecards-ACO2


Protein-protein Interactions for ACO2
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in ACO2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AconitaseA/IPMdHydase_ssu_swvl IPR000573 0
Category members Acoase/IPM_deHydtase_lsu_aba IPR001030 0
Category members Aconitase/3IPM_dehydase_swvl IPR015928 0


Protein complexes (CORUM database) featuring ACO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ACO2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_8 BIOCARTA_KREB_PATHWAY 0 1.35
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_9 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT 0 0.33
Category members GO Category GO:0006102 isocitrate metabolic process Database 0.31
Category members GO Category GO:0003994 aconitate hydratase activity Database 0.17
Category members GO Category GO:0006101 citrate metabolic process Database 0.13
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_7 KEGG_GLYOXYLATE_AND_DICARBOXYLATE_METABOLISM 0 0.08
Category members GO Category GO:0008219 cell death Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0006091 generation of precursor metabolites and energy Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0051538 3 iron, 4 sulfur cluster binding Database 0
Category members GO Category GO:0051539 4 iron, 4 sulfur cluster binding Database 0


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