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Query: IDH3B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IDH3B 0 3.656 0.600 0.900 1.060 1.064 -0.360 0.606 0.386

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for IDH3B:


Pubmed-IDH3B »
Uniprot-IDH3B »
Biogrid-IDH3B »
ProteomicsDB-IDH3B »

Tumorportal-IDH3B »
COSMIC-IDH3B »
GenomeRNAi-IDH3B »
Genecards-IDH3B


Protein-protein Interactions for IDH3B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GDF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IDH3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IDH3B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IDH3B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members IsoPropMal-DH-like_dom IPR024084 0.68
Category members Isocitrate_DH_NAD IPR004434 0.15


Protein complexes (CORUM database) featuring IDH3B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IDH3B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_3 KEGG_CITRATE_CYCLE_TCA_CYCLE 0 3.83
Category members GO Category GO:0006099 tricarboxylic acid cycle Database 2.74
Category members Pathway Pathway_12 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE 0 1.87
Category members Pathway Pathway_10 REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE 0 1.76
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0051287 NAD binding Database 1.6
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0006102 isocitrate metabolic process Database 0.31
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0006734 NADH metabolic process Database 0.26
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_13 REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT 0 0.04
Category members GO Category GO:0009055 electron carrier activity Database 0.02
Category members Disease phenotype Retinitis_pigmentosa Retinitis pigmentosa Database 0
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0004449 isocitrate dehydrogenase (NAD+) activity Database 0
Category members GO Category GO:0006103 2-oxoglutarate metabolic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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