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oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
(GO:0016616)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HIBADH 3 -2.110 4.730 -0.456 2.647 2.520
LDHAL6A 2 -1.750 3.360 -0.305 2.399 -2.477 0.419 0.686
LDHAL6A 2 -1.750 3.360
MAT2B 1 3.010 -1.150
UGDH 1 -2.490 4.330 0.356
LDHB 1 -0.930 0.930 -0.305 2.399 -2.477 0.419 0.686
LDHA 1 0.290 0.240 0.385 2.314 -1.710 0.736 -1.948
IDH1 1 0.390 -0.320 1.581 0.783
HADH 1 -0.250 -0.080 2.056 0.819 0.176
LDHC 1 0.660 0.360
LDHC 1 0.660 0.360 -0.305 2.399 -2.477 0.419 0.686
CTBP2 1 2.270 -1.110
CTBP2 1 2.270 -1.110 1.494 -0.398 0.504 0.897 -0.123
IDH2 1 0.090 -0.520 0.923 -2.210 2.164 1.203
PYCR1 1 -1.990 3.890 -0.387 0.054 -0.369 0.817 0.574
MDH1 0 0.340 -0.770 1.386 0.112
FAR2 0 0.560 0.000
TGDS 0 -0.720 0.410
PHGDH 0 -0.190 -0.280 0.032 -0.024 -0.302 1.449 0.834
IDH3B 0 0.600 0.900 1.060 1.064 -0.360 0.606 0.386
AHCY 0 0.070 -0.370 0.448 0.752 -1.126 0.195 -0.279
HMGCR 0 0.240 0.010
GRHPR 0 -0.600 0.670 -1.778 -0.778
GRHPR 0 -0.600 0.670 0.454
NDUFA9 0 0.390 -0.190 0.726 -0.609 0.138
C1orf43 0 -0.260 0.230
GPD1L 0 -0.160 0.390 -0.064
FAM213B 0 0.610 -1.300
AHCYL2 0 0.290 -0.240 -0.613 0.147 -1.090
AHCYL2 0 0.290 -0.240
CTBP1 0 -0.410 0.390
CTBP1 0 -0.410 0.390 -0.293 -0.875 0.361 0.407 -0.049
CTBP1 0 -0.410 0.390 1.494 -0.398 0.504 0.897 -0.123
IDH3A 0 0.580 -0.500 0.488 1.195 -0.834 0.675 0.445
AHCYL1 0 -0.080 0.400 -0.613 0.147 -1.090
LDHAL6B 0 -0.960 1.510
SDR42E2 0

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AHCY Ubiquitylation K43 0.164 _YSASK(gl)PLK_
AHCY Ubiquitylation K46 0.699 -0.332 _YSASKPLK(gl)GAR_
AHCY Ubiquitylation K186 0.195 -0.162 _VPAINVNDSVTK(gl)SK_
AHCY Ubiquitylation K188 0.784 0.743 _SK(gl)FDNLYGCR_
AHCY Ubiquitylation K204 0.055 -0.020 _ESLIDGIK(gl)R_
AHCY Ubiquitylation K226 0.829 0.442 _VAVVAGYGDVGK(gl)GCAQALR_
AHCY Ubiquitylation K405 0.352 0.515 _LNVK(gl)LTK_
AHCY Ubiquitylation K408 0.040 0.435 _LTK(gl)LTEK_
AHCYL1 Phosphorylation S2 -1.071 0.510 _(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL1 Ubiquitylation K111 0.290 -1.029 _NIK(gl)QAEFGRR_
AHCYL1 Ubiquitylation K267 0.573 _LYQLSK(gl)AGK_
AHCYL2 Phosphorylation S2 -1.071 0.510 _(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL2 Phosphorylation S107 0.835 0.621 _DGGEALVS(ph)PDGTVTEAPR_
AHCYL2 Ubiquitylation K111 0.290 -1.029 _NIK(gl)QAEFGRR_
AHCYL2 Ubiquitylation K267 0.573 _LYQLSK(gl)AGK_
C1orf43 Ubiquitylation K73 -0.830 _VQDIK(gl)YEPQLLADDDAR_
C1orf43 Ubiquitylation K105 0.241 _MK(gl)ALDAIR_
C1orf43 Ubiquitylation K130 0.561 _SLMGK(gl)NFR_
C1orf43 Ubiquitylation K191 0.319 _YQEALSELATAVK(gl)AR_
CTBP1 Ubiquitylation K279 0.443 _GGLVDEK(gl)ALAQALK_
CTBP1 Ubiquitylation K286 0.130 0.008 _ALAQALK(gl)EGR_
CTBP1 Phosphorylation S492 -1.548 _YPPGIVGVAPGGLPAAM(ox)EGIIPGGIPVTHNLPTVAHPS(ph)QAPSPNQPTK_
CTBP2 Ubiquitylation K6 0.873 0.855 _(ac)ALVDK(gl)HK_
CTBP2 Ubiquitylation K279 0.443 _GGLVDEK(gl)ALAQALK_
CTBP2 Ubiquitylation K286 0.130 0.008 _ALAQALK(gl)EGR_
CTBP2 Phosphorylation S492 -1.548 _YPPGIVGVAPGGLPAAM(ox)EGIIPGGIPVTHNLPTVAHPS(ph)QAPSPNQPTK_
FAM213B Ubiquitylation K101 0.342 _QLYK(gl)ELGFK_
FAR2 Ubiquitylation K379 0.174 _MTK(gl)LMNR_
HMGCR Ubiquitylation K142 -0.522 _ASTLAK(gl)FALSSNSQDEVR_
HMGCR Ubiquitylation K248 -3.854 -2.107 _VLEEEENK(gl)PNPVTQR_
HMGCR Ubiquitylation K299 -1.680 -0.460 _VSLGLDENVSK(gl)R_
HMGCR Ubiquitylation K363 -1.750 _NPITSPVVTQKK(gl)_
HMGCR Ubiquitylation K381 -0.848 _NNQK(gl)CDSVEEETGINR_
HMGCR Ubiquitylation K401 -3.050 _KVEVIK(gl)PLVAETDTPNR_
HMGCR Ubiquitylation K502 -1.382 _K(gl)LSEPSSLQYLPYR_
HMGCR Ubiquitylation K633 -1.104 _LQK(gl)LHTSIAGR_
HMGCR Ubiquitylation K662 -1.291 _SGDAMGMNMISK(gl)GTEK_
HMGCR Ubiquitylation K704 -1.716 _GK(gl)SVVCEAVIPAK(gl)VVR_
HMGCR Ubiquitylation K715 -1.982 _SVVCEAVIPAK(gl)VVR_
HMGCR Ubiquitylation K873 -1.345 _SK(gl)INLQDLQGACTKK_
HMGCR Ubiquitylation K885 -1.690 _SKINLQDLQGACTK(gl)K_
HMGCR Ubiquitylation K886 -1.325 _INLQDLQGACTKK(gl)_
IDH1 Ubiquitylation K58 -0.442 0.097 _DATNDQVTK(gl)DAAEAIKK_
IDH3A Ubiquitylation K177 -0.835 _LITEGASK(gl)R_
IDH3A Ubiquitylation K200 -1.507 _SNVTAVHK(gl)ANIMR_
IDH3A Ubiquitylation K214 -0.957 _MSDGLFLQK(gl)CR_
IDH3A Ubiquitylation K336 -0.022 -0.342 _IEAACFATIK(gl)DGK_
IDH3A Ubiquitylation K343 -0.549 _SLTK(gl)DLGGNAK_
LDHA Ubiquitylation K14 -1.168 _DQLIYNLLK(gl)EEQTPQNK_
LDHA Ubiquitylation K76 0.117 0.016 _TPK(gl)IVSGKDYNVTANSK_
LDHA Ubiquitylation K81 -0.222 0.603 _IVSGK(gl)DYNVTANSK_
LDHA Ubiquitylation K118 -0.092 _NVNIFK(gl)FIIPNVVK_
LDHA Ubiquitylation K126 -1.139 -0.426 _FIIPNVVK(gl)YSPNCK_
LDHA Ubiquitylation K317 0.038 _LK(gl)KSADTLWGIQK_
LDHA Ubiquitylation K318 -0.423 -0.142 _K(gl)SADTLWGIQK_
LDHAL6A Ubiquitylation K7 -0.548 _EK(gl)LIAPVAEEEATVPNNK_
LDHAL6A Ubiquitylation K82 0.531 _IVADK(gl)DYSVTANSK_
LDHAL6A Ubiquitylation K155 -0.043 0.105 _LSGFPK(gl)NR_
LDHAL6A Ubiquitylation K308 -0.099 0.921 _GLTSVINQK(gl)LKDDEVAQLK_
LDHAL6A Ubiquitylation K310 0.087 -0.793 _LK(gl)DDEVAQLKK_
LDHAL6A Ubiquitylation K318 -0.094 -1.111 _LKDDEVAQLK(gl)K_
LDHAL6A Ubiquitylation K329 0.419 _SADTLWDIQK(gl)DLKDL_
LDHAL6A Ubiquitylation K332 0.762 _SADTLWDIQKDLK(gl)DL_
LDHAL6B Ubiquitylation K277 -0.200 -0.227 _DPEQWK(gl)NVHK_
LDHB Ubiquitylation K7 -0.548 _EK(gl)LIAPVAEEEATVPNNK_
LDHB Ubiquitylation K82 0.531 _IVADK(gl)DYSVTANSK_
LDHB Ubiquitylation K308 -0.099 0.921 _GLTSVINQK(gl)LKDDEVAQLK_
LDHB Ubiquitylation K310 0.087 -0.793 _LK(gl)DDEVAQLKK_
LDHB Ubiquitylation K318 -0.094 -1.111 _LKDDEVAQLK(gl)K_
LDHB Ubiquitylation K329 0.419 _SADTLWDIQK(gl)DLKDL_
LDHB Ubiquitylation K332 0.762 _SADTLWDIQKDLK(gl)DL_
LDHC Ubiquitylation K5 0.146 _(ac)STVK(gl)EQLIEK_
LDHC Ubiquitylation K7 -0.548 _EK(gl)LIAPVAEEEATVPNNK_
LDHC Ubiquitylation K81 -0.271 _ITSGK(gl)DYSVSANSR_
LDHC Ubiquitylation K82 0.531 _IVADK(gl)DYSVTANSK_
LDHC Ubiquitylation K308 -0.099 0.921 _GLTSVINQK(gl)LKDDEVAQLK_
LDHC Ubiquitylation K310 0.087 -0.793 _LK(gl)DDEVAQLKK_
LDHC Ubiquitylation K318 -0.094 -1.111 _LKDDEVAQLK(gl)K_
LDHC Ubiquitylation K329 0.419 _SADTLWDIQK(gl)DLKDL_
LDHC Ubiquitylation K332 0.762 _SADTLWDIQKDLK(gl)DL_
MAT2B Ubiquitylation K209 -0.298 _VQFSNK(gl)SANMDHWQQR_
MDH1 Ubiquitylation K121 1.157 0.308 _DLLK(gl)ANVK_
MDH1 Ubiquitylation K160 -1.596 _VIVVGNPANTNCLTASK(gl)SAPSIPK_
MDH1 Ubiquitylation K232 -0.046 _EVGVYEALK(gl)DDSWLK_
MDH1 Ubiquitylation K238 -0.272 _EVGVYEALK(gl)DDSWLK_
MDH1 Ubiquitylation K254 -0.543 _GAAVIK(gl)AR_
MDH1 Ubiquitylation K330 0.073 _EK(gl)MDLTAK_
PHGDH Ubiquitylation K21 0.211 0.538 _K(gl)ILQDGGLQVVEK_
PHGDH Ubiquitylation K58 -0.078 0.489 _SATK(gl)VTADVINAAEK_
PHGDH Ubiquitylation K69 0.277 0.839 _VTADVINAAEK(gl)LQVVGR_
PHGDH Ubiquitylation K289 -0.629 -0.819 _ALVDHENVISCPHLGASTK(gl)EAQSR_
PHGDH Ubiquitylation K351 -0.346 0.413 _AWAGSPK(gl)GTIQVITQGTSLK_
PHGDH Ubiquitylation K384 -0.129 -0.044 _EASK(gl)QADVNLVNAK_
PHGDH Ubiquitylation K394 -0.043 _QADVNLVNAK(gl)LLVK_
SDR42E2 Ubiquitylation K30 -0.620 _TQAKPTK(gl)AAR_
TGDS Ubiquitylation K67 -0.169 _NLETISNK(gl)QNYK_
UGDH Phosphorylation S72 1.099 _NLFFS(ph)TNIDDAIK_
UGDH Phosphorylation T73 1.099 _NLFFS(ph)TNIDDAIK_


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