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Query: AHCY

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AHCY 0 1.936 0.070 -0.370 0.448 0.752 -1.126 0.195 -0.279

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AHCY Ubiquitylation K188 0.784 0.743 _SK(gl)FDNLYGCR_
AHCY Ubiquitylation K405 0.352 0.515 _LNVK(gl)LTK_
AHCY Ubiquitylation K226 0.829 0.442 _VAVVAGYGDVGK(gl)GCAQALR_
AHCY Ubiquitylation K408 0.040 0.435 _LTK(gl)LTEK_
AHCY Ubiquitylation K43 0.164 _YSASK(gl)PLK_
AHCY Ubiquitylation K204 0.055 -0.020 _ESLIDGIK(gl)R_
AHCY Ubiquitylation K186 0.195 -0.162 _VPAINVNDSVTK(gl)SK_
AHCY Ubiquitylation K46 0.699 -0.332 _YSASKPLK(gl)GAR_

Background Information for AHCY:


Pubmed-AHCY »
Uniprot-AHCY »
Biogrid-AHCY »
ProteomicsDB-AHCY »

Tumorportal-AHCY »
COSMIC-AHCY »
GenomeRNAi-AHCY »
Genecards-AHCY


Protein-protein Interactions for AHCY
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AHCY Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AHCY
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Adenosylhomocysteinase IPR000043 0.05
Category members Ado_hCys_hydrolase_NAD-bd IPR015878 0.05
Category members D-isomer_DH_NAD-bd IPR006140 0.03
Category members IlvN IPR013116 0


Protein complexes (CORUM database) featuring AHCY
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AHCY
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0042470 melanosome Database 5.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members GO Category GO:0004013 adenosylhomocysteinase activity Database 0.05
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_399 REACTOME_SULFUR_AMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0004455 ketol-acid reductoisomerase activity Database 0
Category members GO Category GO:0006730 one-carbon metabolic process Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0008652 cellular amino acid biosynthetic process Database 0
Category members GO Category GO:0032259 methylation Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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