RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
DNMT1	2	0.150	-0.150		0.077	-0.109	-1.422	0.572
DNMT1	2	0.150	-0.150	0.134			-0.347	-0.054
LDHAL6A	2	-1.750	3.360	-0.305	2.399	-2.477	0.419	0.686
LDHAL6A	2	-1.750	3.360
MAT2B	1	3.010	-1.150
LDHB	1	-0.930	0.930	-0.305	2.399	-2.477	0.419	0.686
SRM	1	1.420	-1.060	0.631			1.832	0.593
GOT2	1	0.300	-0.690
GOT2	1	0.300	-0.690		2.371	-3.377	1.219	0.447
LDHA	1	0.290	0.240	0.385	2.314	-1.710	0.736	-1.948
CBS	1	-1.310	2.540	0.002				-0.255
LDHC	1	0.660	0.360
LDHC	1	0.660	0.360	-0.305	2.399	-2.477	0.419	0.686
DNMT3B	0	0.990	-0.100				0.783	0.015
MTAP	0	1.310	-0.900
AHCY	0	0.070	-0.370	0.448	0.752	-1.126	0.195	-0.279
CTH	0	1.680	-1.070
MTR	0	-0.880	0.640
GOT1	0	-0.320	0.110
AMD1	0	1.390	-0.600
MPST	0	-0.290	0.000		1.318
CDO1	0	-0.540	0.620
APIP	0	-0.210	-0.260
APIP	0	1.370	-0.480
AHCYL2	0	0.290	-0.240	-0.613	0.147	-1.090
AHCYL2	0	0.290	-0.240
AHCYL1	0	-0.080	0.400	-0.613	0.147	-1.090
MAT2A	0	0.240	-0.710		-2.433	1.061	0.253	-0.678
LDHAL6B	0	-0.960	1.510

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AHCY	Ubiquitylation	K43		0.164	_YSASK(gl)PLK_
AHCY	Ubiquitylation	K46	0.699	-0.332	_YSASKPLK(gl)GAR_
AHCY	Ubiquitylation	K186	0.195	-0.162	_VPAINVNDSVTK(gl)SK_
AHCY	Ubiquitylation	K188	0.784	0.743	_SK(gl)FDNLYGCR_
AHCY	Ubiquitylation	K204	0.055	-0.020	_ESLIDGIK(gl)R_
AHCY	Ubiquitylation	K226	0.829	0.442	_VAVVAGYGDVGK(gl)GCAQALR_
AHCY	Ubiquitylation	K405	0.352	0.515	_LNVK(gl)LTK_
AHCY	Ubiquitylation	K408	0.040	0.435	_LTK(gl)LTEK_
AHCYL1	Phosphorylation	S2	-1.071	0.510	_(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL1	Ubiquitylation	K111	0.290	-1.029	_NIK(gl)QAEFGRR_
AHCYL1	Ubiquitylation	K267	0.573		_LYQLSK(gl)AGK_
AHCYL2	Phosphorylation	S2	-1.071	0.510	_(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL2	Phosphorylation	S107	0.835	0.621	_DGGEALVS(ph)PDGTVTEAPR_
AHCYL2	Ubiquitylation	K111	0.290	-1.029	_NIK(gl)QAEFGRR_
AHCYL2	Ubiquitylation	K267	0.573		_LYQLSK(gl)AGK_
AMD1	Ubiquitylation	K201		-1.024	_DGVTAK(gl)DVTR_
AMD1	Ubiquitylation	K291	-0.884	-0.830	_FVTTLFVNQSSK(gl)CR_
AMD1	Ubiquitylation	K301		-1.418	_TVLASPQK(gl)IEGFKR_
AMD1	Ubiquitylation	K306		-1.912	_TVLASPQKIEGFK(gl)R_
APIP	Phosphorylation	S104	-0.232	-0.421	_DISGPS(ph)PSK_
CBS	Phosphorylation	S32		0.298	_GSLEKGS(ph)PEDKEAK_
CBS	Ubiquitylation	K177		-2.211	_MSSEK(gl)VDVLR_
CBS	Ubiquitylation	K481	-0.474	-0.347	_VQPSDQVGK(gl)VIYK_
CBS	Ubiquitylation	K485		-0.140	_VIYK(gl)QFK_
CDO1	Ubiquitylation	K8	-2.513	-0.979	_(ac)MEQTEVLK(gl)PR_
CTH	Ubiquitylation	K73		-0.035	_NCLEK(gl)AVAALDGAK_
DNMT1	Phosphorylation	S127	-0.755	-0.836	_VGM(ox)ADANS(ph)PPKPLSKPR_
DNMT1	Phosphorylation	S143	0.877	0.220	_SKS(ph)DGEAKPEPSPSPR_
DNMT1	Phosphorylation	S152	-0.685	-1.347	_SDGEAKPEPS(ph)PSPR_
DNMT1	Phosphorylation	S154	-1.926	-0.876	_SDGEAKPEPSPS(ph)PR_
DNMT1	Ubiquitylation	K586	1.686	3.368	_DLIK(gl)LAGVTLGQR_
DNMT1	Ubiquitylation	K675	1.267	0.915	_DMVK(gl)FGGSGR_
DNMT1	Phosphorylation	S714	-0.773	-0.554	_EADDDEEVDDNIPEMPS(ph)PKK_
DNMT1	Phosphorylation	S954	-0.318	0.057	_LSS(ph)PVKRPR_
DNMT1	Ubiquitylation	K961	-3.166		_K(gl)EPVDEDLYPEHYR_
DNMT1	Ubiquitylation	K981	-0.298	-1.482	_YSDYIK(gl)GSNLDAPEPYR_
DNMT1	Ubiquitylation	K997	0.042	0.154	_IK(gl)EIFCPK_
DNMT1	Ubiquitylation	K1483	1.983	-0.103	_GVCSCVEAGK(gl)ACDPAAR_
DNMT3B	Ubiquitylation	K597	0.236		_ELGIK(gl)VGK_
DNMT3B	Ubiquitylation	K623	0.433		_HEGNIK(gl)YVNDVR_
GOT1	Ubiquitylation	K97		-0.580	_LALGDDSPALK(gl)EK_
GOT2	Ubiquitylation	K321		-1.209	_TQLVSNLKK(gl)_
LDHA	Ubiquitylation	K14	-1.168		_DQLIYNLLK(gl)EEQTPQNK_
LDHA	Ubiquitylation	K76	0.117	0.016	_TPK(gl)IVSGKDYNVTANSK_
LDHA	Ubiquitylation	K81	-0.222	0.603	_IVSGK(gl)DYNVTANSK_
LDHA	Ubiquitylation	K118	-0.092		_NVNIFK(gl)FIIPNVVK_
LDHA	Ubiquitylation	K126	-1.139	-0.426	_FIIPNVVK(gl)YSPNCK_
LDHA	Ubiquitylation	K317	0.038		_LK(gl)KSADTLWGIQK_
LDHA	Ubiquitylation	K318	-0.423	-0.142	_K(gl)SADTLWGIQK_
LDHAL6A	Ubiquitylation	K7		-0.548	_EK(gl)LIAPVAEEEATVPNNK_
LDHAL6A	Ubiquitylation	K82		0.531	_IVADK(gl)DYSVTANSK_
LDHAL6A	Ubiquitylation	K155	-0.043	0.105	_LSGFPK(gl)NR_
LDHAL6A	Ubiquitylation	K308	-0.099	0.921	_GLTSVINQK(gl)LKDDEVAQLK_
LDHAL6A	Ubiquitylation	K310	0.087	-0.793	_LK(gl)DDEVAQLKK_
LDHAL6A	Ubiquitylation	K318	-0.094	-1.111	_LKDDEVAQLK(gl)K_
LDHAL6A	Ubiquitylation	K329		0.419	_SADTLWDIQK(gl)DLKDL_
LDHAL6A	Ubiquitylation	K332	0.762		_SADTLWDIQKDLK(gl)DL_
LDHAL6B	Ubiquitylation	K277	-0.200	-0.227	_DPEQWK(gl)NVHK_
LDHB	Ubiquitylation	K7		-0.548	_EK(gl)LIAPVAEEEATVPNNK_
LDHB	Ubiquitylation	K82		0.531	_IVADK(gl)DYSVTANSK_
LDHB	Ubiquitylation	K308	-0.099	0.921	_GLTSVINQK(gl)LKDDEVAQLK_
LDHB	Ubiquitylation	K310	0.087	-0.793	_LK(gl)DDEVAQLKK_
LDHB	Ubiquitylation	K318	-0.094	-1.111	_LKDDEVAQLK(gl)K_
LDHB	Ubiquitylation	K329		0.419	_SADTLWDIQK(gl)DLKDL_
LDHB	Ubiquitylation	K332	0.762		_SADTLWDIQKDLK(gl)DL_
LDHC	Ubiquitylation	K5		0.146	_(ac)STVK(gl)EQLIEK_
LDHC	Ubiquitylation	K7		-0.548	_EK(gl)LIAPVAEEEATVPNNK_
LDHC	Ubiquitylation	K81		-0.271	_ITSGK(gl)DYSVSANSR_
LDHC	Ubiquitylation	K82		0.531	_IVADK(gl)DYSVTANSK_
LDHC	Ubiquitylation	K308	-0.099	0.921	_GLTSVINQK(gl)LKDDEVAQLK_
LDHC	Ubiquitylation	K310	0.087	-0.793	_LK(gl)DDEVAQLKK_
LDHC	Ubiquitylation	K318	-0.094	-1.111	_LKDDEVAQLK(gl)K_
LDHC	Ubiquitylation	K329		0.419	_SADTLWDIQK(gl)DLKDL_
LDHC	Ubiquitylation	K332	0.762		_SADTLWDIQKDLK(gl)DL_
MAT2A	Ubiquitylation	K81	0.110	0.137	_AAVDYQK(gl)VVR_
MAT2A	Ubiquitylation	K163		-0.321	_LNAK(gl)LAELRR_
MAT2A	Ubiquitylation	K228	-0.689	-0.376	_VIK(gl)AVVPAK_
MAT2A	Ubiquitylation	K234	-0.386		_AVVPAK(gl)YLDEDTIYHLQPSGR_
MAT2A	Ubiquitylation	K289		-0.395	_DYTK(gl)VDR_
MAT2A	Ubiquitylation	K303		-0.265	_WVAK(gl)SLVK_
MAT2A	Ubiquitylation	K307	-0.195	0.870	_SLVK(gl)GGLCR_
MAT2A	Ubiquitylation	K350	0.414	0.274	_ELLEIVK(gl)K_
MAT2A	Ubiquitylation	K351	-0.735		_K(gl)NFDLRPGVIVR_
MAT2A	Ubiquitylation	K367	-0.930	-1.508	_DLDLK(gl)KPIYQR_
MAT2A	Ubiquitylation	K368		-0.719	_DLDLK(gl)KPIYQR_
MAT2B	Ubiquitylation	K209	-0.298		_VQFSNK(gl)SANMDHWQQR_
MPST	Phosphorylation	S15		0.341	_S(ph)PSVAAMASPQLCR_
MPST	Phosphorylation	S17	1.337		_SPS(ph)VAAMASPQLCR_
MPST	Ubiquitylation	K166		-1.712	_QNLPLSSGK(gl)SQPAPAEFR_
MTAP	Ubiquitylation	K57	-0.883		_YVDTPFGK(gl)PSDALILGK_
MTAP	Ubiquitylation	K174		-0.133	_EVLIETAK(gl)K_
MTAP	Ubiquitylation	K175	0.382		_EVLIETAKK(gl)_
MTR	Ubiquitylation	K139		-1.097	_KAAEEVTLQTGIK(gl)R_
MTR	Ubiquitylation	K151		-1.770	_FVAGALGPTNK(gl)TLSVSPSVERPDYR_
MTR	Ubiquitylation	K735		-1.046	_MFLPQVIK(gl)SAR_
MTR	Ubiquitylation	K814		-0.284	_VIDLGVMTPCDK(gl)ILK_
MTR	Ubiquitylation	K817	-1.172	-0.641	_ILK(gl)AALDHK_
MTR	Ubiquitylation	K865		-0.805	_IPLLIGGATTSK(gl)THTAVK_
MTR	Ubiquitylation	K1000	-0.505	-0.872	_IFNDK(gl)TVGGEAR_