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Query: CTH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CTH 0 -0.035 1.680 -1.070

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CTH Ubiquitylation K73 -0.035 _NCLEK(gl)AVAALDGAK_

Background Information for CTH:


Pubmed-CTH »
Uniprot-CTH »
Biogrid-CTH »
ProteomicsDB-CTH »

Tumorportal-CTH »
COSMIC-CTH »
GenomeRNAi-CTH »
Genecards-CTH


Protein-protein Interactions for CTH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FSD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GHITM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUM Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCRA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RDH12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCG3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A32 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLC25A41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPRY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM223 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF434 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF488 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CTH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Aminotrans_V_dom IPR000192 0
Category members Cys/Met-Metab_PyrdxlP-dep_enz IPR000277 0
Category members DegT/StrS_aminotransferase IPR000653 0
Category members Aminotransferase_I/II IPR004839 0
Category members PyrdxlP-dep_Trfase IPR015424 0


Protein complexes (CORUM database) featuring CTH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CTH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0005516 calmodulin binding Database 0.74
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0051289 protein homotetramerization Database 0.44
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members Pathway Pathway_393 KEGG_NITROGEN_METABOLISM 0 0.07
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_20 KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_399 REACTOME_SULFUR_AMINO_ACID_METABOLISM 0 0
Category members GO Category GO:0000098 sulfur amino acid catabolic process Database 0
Category members GO Category GO:0006534 cysteine metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016846 carbon-sulfur lyase activity Database 0
Category members GO Category GO:0019344 cysteine biosynthetic process Database 0
Category members GO Category GO:0019346 transsulfuration Database 0
Category members GO Category GO:0030170 pyridoxal phosphate binding Database 0
Category members GO Category GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0
Category members GO Category GO:0070814 hydrogen sulfide biosynthetic process Database 0


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