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Query: CBS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CBS 1 1.971 -1.310 2.540 0.002 -0.255

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CBS Phosphorylation S32 0.298 _GSLEKGS(ph)PEDKEAK_
CBS Ubiquitylation K485 -0.140 _VIYK(gl)QFK_
CBS Ubiquitylation K481 -0.474 -0.347 _VQPSDQVGK(gl)VIYK_
CBS Ubiquitylation K177 -2.211 _MSSEK(gl)VDVLR_

Background Information for CBS:


Pubmed-CBS »
Uniprot-CBS »
Biogrid-CBS »
ProteomicsDB-CBS »

Tumorportal-CBS »
COSMIC-CBS »
GenomeRNAi-CBS »
Genecards-CBS


Protein-protein Interactions for CBS
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in CBS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members CBS_dom IPR000644 0
Category members TrpB-like_PLP-dep IPR001926 0


Protein complexes (CORUM database) featuring CBS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CBS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0043506 regulation of JUN kinase activity Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members GO Category GO:0001958 endochondral ossification Database 0.04
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0020037 heme binding Database 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_20 KEGG_GLYCINE_SERINE_AND_THREONINE_METABOLISM 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_399 REACTOME_SULFUR_AMINO_ACID_METABOLISM 0 0
Category members GO Category GO:0001974 blood vessel remodeling Database 0
Category members GO Category GO:0006563 L-serine metabolic process Database 0
Category members GO Category GO:0006565 L-serine catabolic process Database 0
Category members GO Category GO:0006801 superoxide metabolic process Database 0
Category members GO Category GO:0019344 cysteine biosynthetic process Database 0
Category members GO Category GO:0019346 transsulfuration Database 0
Category members GO Category GO:0019448 L-cysteine catabolic process Database 0
Category members GO Category GO:0021587 cerebellum morphogenesis Database 0
Category members GO Category GO:0030170 pyridoxal phosphate binding Database 0
Category members GO Category GO:0030554 adenyl nucleotide binding Database 0
Category members GO Category GO:0030823 regulation of cGMP metabolic process Database 0
Category members GO Category GO:0031667 response to nutrient levels Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0050667 homocysteine metabolic process Database 0
Category members GO Category GO:0050880 regulation of blood vessel size Database 0
Category members GO Category GO:0060135 maternal process involved in female pregnancy Database 0
Category members GO Category GO:0060351 cartilage development involved in endochondral bone morphogenesis Database 0
Category members GO Category GO:0070814 hydrogen sulfide biosynthetic process Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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