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Query: MAT2B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MAT2B 1 -0.298 3.010 -1.150

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MAT2B Ubiquitylation K209 -0.298 _VQFSNK(gl)SANMDHWQQR_

Background Information for MAT2B:


Pubmed-MAT2B »
Uniprot-MAT2B »
Biogrid-MAT2B »
ProteomicsDB-MAT2B »

Tumorportal-MAT2B »
COSMIC-MAT2B »
GenomeRNAi-MAT2B »
Genecards-MAT2B


Protein-protein Interactions for MAT2B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAT1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in MAT2B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Epimerase_deHydtase_N IPR001509 0
Category members 3Beta_OHSteriod_DH/Estase IPR002225 0
Category members Polysac_CapD-like IPR003869 0
Category members dTDP_dehydrorham_reduct IPR005913 0
Category members Male_sterile_NAD-bd IPR013120 0


Protein complexes (CORUM database) featuring MAT2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MAT2B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0006694 steroid biosynthetic process Database 0.29
Category members GO Category GO:0000096 sulfur amino acid metabolic process Database 0.15
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members GO Category GO:0044237 cellular metabolic process Database 0.08
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_399 REACTOME_SULFUR_AMINO_ACID_METABOLISM 0 0
Category members Pathway Pathway_82 REACTOME_PHASE_II_CONJUGATION 0 0
Category members Pathway Pathway_85 REACTOME_BIOLOGICAL_OXIDATIONS 0 0
Category members GO Category GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity Database 0
Category members GO Category GO:0006556 S-adenosylmethionine biosynthetic process Database 0
Category members GO Category GO:0006730 one-carbon metabolic process Database 0
Category members GO Category GO:0006805 xenobiotic metabolic process Database 0
Category members GO Category GO:0008831 dTDP-4-dehydrorhamnose reductase activity Database 0
Category members GO Category GO:0032259 methylation Database 0
Category members GO Category GO:0045226 extracellular polysaccharide biosynthetic process Database 0
Category members GO Category GO:0050662 coenzyme binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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