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Query: AHCYL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
AHCYL1 0 -2.174 -0.080 0.400 -0.613 0.147 -1.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
AHCYL1 Phosphorylation S2 -1.071 0.510 _(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL1 Ubiquitylation K111 0.290 -1.029 _NIK(gl)QAEFGRR_
AHCYL1 Ubiquitylation K267 0.573 _LYQLSK(gl)AGK_

Background Information for AHCYL1:


Pubmed-AHCYL1 »
Uniprot-AHCYL1 »
Biogrid-AHCYL1 »
ProteomicsDB-AHCYL1 »

Tumorportal-AHCYL1 »
COSMIC-AHCYL1 »
GenomeRNAi-AHCYL1 »
Genecards-AHCYL1


Protein-protein Interactions for AHCYL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABCF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AHCY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AHCYL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CEP72 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DHX8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DOK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM13C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEXIM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HOXC9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JOSD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PITX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RASL10B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGIF2LY Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZC3H3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF414 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF444 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in AHCYL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Adenosylhomocysteinase IPR000043 0.05
Category members Ado_hCys_hydrolase_NAD-bd IPR015878 0.05
Category members D-isomer_DH_NAD-bd IPR006140 0.03
Category members IlvN IPR013116 0


Protein complexes (CORUM database) featuring AHCYL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring AHCYL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Database 0.29
Category members GO Category GO:0006378 mRNA polyadenylation Database 0.1
Category members GO Category GO:0048037 cofactor binding Database 0.08
Category members GO Category GO:0004013 adenosylhomocysteinase activity Database 0.05
Category members Pathway Pathway_400 KEGG_CYSTEINE_AND_METHIONINE_METABOLISM 0 0.04
Category members Pathway Pathway_299 KEGG_SELENOAMINO_ACID_METABOLISM 0 0
Category members GO Category GO:0004455 ketol-acid reductoisomerase activity Database 0
Category members GO Category GO:0006611 protein export from nucleus Database 0
Category members GO Category GO:0006730 one-carbon metabolic process Database 0
Category members GO Category GO:0008652 cellular amino acid biosynthetic process Database 0
Category members GO Category GO:0010765 positive regulation of sodium ion transport Database 0
Category members GO Category GO:0044070 regulation of anion transport Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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