RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
PAF1	1	0.390	-0.320	1.232	0.546	1.561	-0.837	0.458
PAPOLA	1	-1.510	2.810
PAPOLG	1	-0.580	0.790
CDC73	1	1.000	-0.660	1.109	0.620	1.610	-0.862	0.436
LEO1	1	-0.730	0.200	1.072	0.738	1.390	1.163	0.646
PABPC1	0	0.100	-0.400	0.167	-0.387	-0.147	-0.312	-0.037
CSTF1	0	0.350	-0.880	0.804			-0.169	0.601
CSTF2	0			-0.939	-0.663	0.068	-0.442	-0.123
MTPAP	0	0.330	-0.610	-1.406	-0.249	-0.194	-0.156	-0.001
CPSF6	0	-0.660	0.180	1.002	0.250	0.499	0.312	-0.256
CPSF3	0	0.760	-0.720	-0.001	-0.206	0.455	-0.433	0.066
SYMPK	0	-0.610	1.280	-0.489	0.051	-0.040	-0.388	0.104
GRSF1	0	1.010	-0.710	0.775	0.625	-0.778	-0.386	-0.048
APP	0	0.100	-0.260					0.285
SSU72	0	1.030	-0.450
CPSF2	0	0.150	0.340	-0.113	-0.032	0.570	0.441	0.355
NUDT21	0	-0.700	0.830	0.214	-0.359	0.236	0.333	0.307
AHCYL1	0	-0.080	0.400	-0.613	0.147	-1.090
CSTF3	0	-1.060	1.590	-0.198	-0.392	0.251	-0.683	-0.064
PAPOLB	0	-1.500	2.280

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
AHCYL1	Phosphorylation	S2	-1.071	0.510	_(ac)S(ph)M(ox)PDAM(ox)PLPGVGEELK_
AHCYL1	Ubiquitylation	K111	0.290	-1.029	_NIK(gl)QAEFGRR_
AHCYL1	Ubiquitylation	K267	0.573		_LYQLSK(gl)AGK_
APP	Ubiquitylation	K751	-1.778	-1.280	_HLSK(gl)M(ox)QQNGYENPTYK_
CDC73	Ubiquitylation	K136	0.034		_AADEVLAEAK(gl)KPR_
CDC73	Ubiquitylation	K161	1.275		_LEGHK(gl)EGIVQTEQIR_
CDC73	Ubiquitylation	K198	0.681		_STIK(gl)TDLDDDITALK_
CDC73	Ubiquitylation	K209	-0.003	-1.671	_TDLDDDITALK(gl)QR_
CDC73	Ubiquitylation	K243	0.937		_TTILQSTGK(gl)NFSK_
CDC73	Ubiquitylation	K247	0.739		_TTILQSTGKNFSK(gl)_
CDC73	Ubiquitylation	K283	-0.189		_TK(gl)QPIPAAYNR_
CPSF2	Ubiquitylation	K140		-0.692	_FSQIVNLKGK(gl)_
CPSF2	Ubiquitylation	K324	-1.406	-1.082	_VPSPK(gl)VVLASQPDLECGFSR_
CPSF2	Ubiquitylation	K725		0.157	_LSDFK(gl)QVLLR_
CPSF3	Ubiquitylation	K348	0.384		_ELFESWCTDK(gl)R_
CPSF3	Ubiquitylation	K428	0.656	0.535	_LK(gl)AALIR_
CPSF3	Ubiquitylation	K465	0.422		_NTEAVTLNFRGEKLAK(gl)_
CPSF3	Ubiquitylation	K474	-0.536		_VMGFLADKK(gl)PEQGQR_
CPSF3	Ubiquitylation	K487	0.072	0.155	_VSGILVK(gl)R_
CPSF3	Ubiquitylation	K604	-0.159		_K(gl)LEMHVYSK_
CPSF6	Ubiquitylation	K79	-0.081		_GAAPNVVYTYTGK(gl)R_
CPSF6	Ubiquitylation	K138	0.018		_GFALVGVGSEASSK(gl)K_
CPSF6	Ubiquitylation	K139	-0.782		_GFALVGVGSEASSKK(gl)_
CPSF6	Ubiquitylation	K185	-0.516	-0.824	_TTQSGQMSGEGK(gl)AGPPGGSSR_
CPSF6	Phosphorylation	T404	1.179	1.083	_EMDT(ph)ARTPLSEAEFEEIMNR_
CPSF6	Phosphorylation	T407	1.386	1.306	_EMDTART(ph)PLSEAEFEEIMNR_
CSTF1	Ubiquitylation	K208		0.139	_LFDYSKPSAK(gl)R_
CSTF1	Ubiquitylation	K326		0.325	_YILSSGK(gl)DSVAK_
CSTF2	Ubiquitylation	K55	-0.926		_LVYDRETGK(gl)PK_
CSTF2	Ubiquitylation	K96	-0.716		_VDNAASEK(gl)NKEELK_
CSTF2	Ubiquitylation	K98	-0.716		_VDNAASEK(gl)NKEELK_
CSTF2	Ubiquitylation	K148	0.429	0.722	_QMK(gl)LCVQNSPQEAR_
CSTF2	Phosphorylation	S538		-1.435	_QVPVMQGTGMQGASIQGGS(ph)QPGGFSPGQNQVTPQDHEK_
CSTF2	Ubiquitylation	K592	-0.132		_EQIQK(gl)STGAP_
CSTF3	Phosphorylation	S2		0.874	_(ac)S(ph)GDGATEQAAEYVPEK_
CSTF3	Ubiquitylation	K17		-0.812	_(ac)SGDGATEQAAEYVPEK(gl)VK_
CSTF3	Ubiquitylation	K19		-0.812	_(ac)SGDGATEQAAEYVPEK(gl)VK_
CSTF3	Ubiquitylation	K49	-1.513	0.082	_EAQNQPIDK(gl)AR_
CSTF3	Phosphorylation	S691	-0.393	-0.297	_RPNEDS(ph)DEDEEKGAVVPPVHDIYR_
GRSF1	Ubiquitylation	K242	0.232	-0.120	_SLQVK(gl)SSPVVNDGVVR_
LEO1	Phosphorylation	S10		0.712	_(ac)ADMEDLFGS(ph)DADSEAER_
LEO1	Phosphorylation	S14		1.186	_(ac)ADMEDLFGSDADS(ph)EAER_
LEO1	Ubiquitylation	K415	1.075		_LK(gl)VENTIR_
LEO1	Ubiquitylation	K486	1.353		_QGTGLQGQAVFK(gl)TK_
LEO1	Ubiquitylation	K503	1.640		_K(gl)MTLSLADR_
LEO1	Ubiquitylation	K537	0.452		_TEMIK(gl)KEEER_
LEO1	Phosphorylation	T629		0.613	_KLT(ph)SDEEGEPSGK_
LEO1	Phosphorylation	S630	0.373	0.499	_LTS(ph)DEEGEPSGK_
LEO1	Phosphorylation	S658	0.549	0.449	_YVIS(ph)DEEEEDDD_
MTPAP	Ubiquitylation	K205		-0.626	_EFQLTEENTK(gl)LR_
MTPAP	Ubiquitylation	K497		-0.857	_NVSQSQLQK(gl)FVDLAR_
NUDT21	Ubiquitylation	K29	-0.121	-0.076	_YIQQTK(gl)PLTLER_
NUDT21	Ubiquitylation	K56	-1.058	0.450	_EPLYEK(gl)DSSVAAR_
NUDT21	Ubiquitylation	K73	0.158		_MREEFDK(gl)IGMR_
NUDT21	Ubiquitylation	K122	-1.445		_LPGGELNPGEDEVEGLK(gl)R_
NUDT21	Ubiquitylation	K189	-0.510		_ALFAVPK(gl)NYK_
NUDT21	Ubiquitylation	K192	-0.730	-0.836	_ALFAVPKNYK(gl)_
PABPC1	Ubiquitylation	K78	-0.883	0.807	_ALDTMNFDVIK(gl)GKPVR_
PABPC1	Ubiquitylation	K95	-0.105	0.553	_K(gl)SGVGNIFIK_
PABPC1	Ubiquitylation	K104	-0.977	-0.336	_SGVGNIFIK(gl)NLDK_
PABPC1	Ubiquitylation	K108	-0.071	0.530	_NLDK(gl)SIDNK_
PABPC1	Ubiquitylation	K138	-0.960		_VVCDENGSK(gl)GYGFVHFETQEAAER_
PABPC1	Ubiquitylation	K157	-0.582		_AIEK(gl)MNGMLLNDRK_
PABPC1	Ubiquitylation	K188	-0.826	-0.017	_AK(gl)EFTNVYIK_
PABPC1	Ubiquitylation	K213	-0.170		_DLFGK(gl)FGPALSVK_
PABPC1	Ubiquitylation	K231	0.080		_SK(gl)GFGFVSFER_
PABPC1	Ubiquitylation	K259	-0.125		_ELNGK(gl)QIYVGR_
PABPC1	Ubiquitylation	K279	-0.143	0.326	_K(gl)FEQMK(gl)QDR_
PABPC1	Ubiquitylation	K284	-0.108	0.322	_K(gl)FEQMK(gl)QDR_
PABPC1	Ubiquitylation	K312	0.122		_K(gl)EFSPFGTITSAK_
PABPC1	Ubiquitylation	K361	-0.142		_IVATK(gl)PLYVALAQR_
PABPC1	Ubiquitylation	K512	-0.640	0.085	_TVPQYK(gl)YAAGVR_
PAF1	Ubiquitylation	K62	-0.086	-0.282	_FVQYK(gl)ATSLEK_
PAF1	Ubiquitylation	K119		-1.018	_LLEEEIQAPTSSK(gl)R_
PAF1	Ubiquitylation	K133		0.847	_K(gl)TEYISTEFNR_
PAF1	Ubiquitylation	K188		-1.529	_TFEDAQK(gl)SISQHYSKPR_
PAF1	Ubiquitylation	K196	-1.455	-1.126	_SISQHYSK(gl)PR_
PAF1	Ubiquitylation	K300	-1.882	-0.738	_EYNWNVK(gl)NK_
PAF1	Ubiquitylation	K338	0.621	-0.090	_AK(gl)AGVQSGTNALLVVK_
PAF1	Ubiquitylation	K352	-0.333	-0.469	_AGVQSGTNALLVVK(gl)HR_
PAPOLA	Phosphorylation	T39	-0.241	0.026	_HYGIT(ph)SPISLAAPK_
PAPOLA	Phosphorylation	S40	0.114	1.106	_HYGITS(ph)PISLAAPK_
PAPOLA	Ubiquitylation	K160		-0.269	_LQEEVK(gl)DLR_
PAPOLA	Phosphorylation	S553		0.479	_LTALNDSSLDLSM(ox)DSDNSM(ox)SVPS(ph)PTSATK_
PAPOLB	Ubiquitylation	K160		-0.269	_LQEEVK(gl)DLR_
PAPOLG	Phosphorylation	S525		1.185	_RLS(ph)LDSSCLDSSR_
PAPOLG	Phosphorylation	S599	-0.230	-0.471	_TVS(ph)PPTVCTIPTVVGR_
PAPOLG	Phosphorylation	S648		0.316	_SHS(ph)PSIDGTPK_
PAPOLG	Phosphorylation	S708	2.392	-0.153	_RLPS(ph)KELPDSSSPVPANNIR_
SSU72	Ubiquitylation	K28	-0.190	0.633	_SMEAHNILSK(gl)R_
SYMPK	Ubiquitylation	K490	-0.556	-1.231	_TESVLIK(gl)R_
SYMPK	Phosphorylation	S494	0.456	-0.279	_RLS(ph)AQGQAISVVGSLSSMSPLEEEAPQAK_
SYMPK	Phosphorylation	S501	0.517	-0.005	_RLSAQGQAIS(ph)VVGSLSSMSPLEEEAPQAK_
SYMPK	Ubiquitylation	K551	-0.114		_LSDVLK(gl)PLTDAQVEAMK_
SYMPK	Ubiquitylation	K1040	0.447	0.966	_VWEGFIK(gl)CCQR_
SYMPK	Phosphorylation	S1170	-0.325		_LKPGGVGAPSSS(ph)SPSPSPSAR_
SYMPK	Phosphorylation	S1171	-0.647	-0.147	_LKPGGVGAPSSSS(ph)PSPSPSAR_
SYMPK	Phosphorylation	S1173	1.053	-2.091	_LKPGGVGAPSSSSPS(ph)PSPSAR_
SYMPK	Phosphorylation	T1231	0.104	-0.160	_ET(ph)AAGGLTLKEERSPQTLAPVGEDAMK_
SYMPK	Phosphorylation	T1237	0.076		_ETAAGGLT(ph)LKEERSPQTLAPVGEDAM(ox)K_
SYMPK	Phosphorylation	S1243	0.014	-0.294	_S(ph)PQTLAPVGEDAM(ox)K_
SYMPK	Phosphorylation	S1259	-0.172	-1.286	_TPS(ph)PAAEDAREPEAK_