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Query: PAF1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAF1 1 4.428 0.390 -0.320 1.232 0.546 1.561 -0.837 0.458

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAF1 Ubiquitylation K133 0.847 _K(gl)TEYISTEFNR_
PAF1 Ubiquitylation K338 0.621 -0.090 _AK(gl)AGVQSGTNALLVVK_
PAF1 Ubiquitylation K62 -0.086 -0.282 _FVQYK(gl)ATSLEK_
PAF1 Ubiquitylation K352 -0.333 -0.469 _AGVQSGTNALLVVK(gl)HR_
PAF1 Ubiquitylation K300 -1.882 -0.738 _EYNWNVK(gl)NK_
PAF1 Ubiquitylation K119 -1.018 _LLEEEIQAPTSSK(gl)R_
PAF1 Ubiquitylation K196 -1.455 -1.126 _SISQHYSK(gl)PR_
PAF1 Ubiquitylation K188 -1.529 _TFEDAQK(gl)SISQHYSKPR_

Background Information for PAF1:


Pubmed-PAF1 »
Uniprot-PAF1 »
Biogrid-PAF1 »
ProteomicsDB-PAF1 »

Tumorportal-PAF1 »
COSMIC-PAF1 »
GenomeRNAi-PAF1 »
Genecards-PAF1


Protein-protein Interactions for PAF1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC73 Cat. description Hein, Mann, Cell 2015
Category members IP bait CTR9 Cat. description Hein, Mann, Cell 2015
Category members IP bait LEO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2G Cat. description Hein, Mann, Cell 2015
Category members IP bait RPRD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SUPT5H Cat. description Hein, Mann, Cell 2015
Category members IP bait TOX4 Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR61 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARL4C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDC73 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HNRPLL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYLIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YAF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAF1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring PAF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1167 Paf complex Database 1.75


Categories featuring PAF1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0001711 endodermal cell fate commitment Database 2.34
Category members GO Category GO:0016593 Cdc73/Paf1 complex Database 1.75
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0010390 histone monoubiquitination Database 1.39
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter Database 0.99
Category members GO Category GO:0000993 RNA polymerase II core binding Database 0.91
Category members GO Category GO:0033523 histone H2B ubiquitination Database 0.77
Category members GO Category GO:0031442 positive regulation of mRNA 3'-end processing Database 0.7
Category members GO Category GO:0019827 stem cell maintenance Database 0.48
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0016055 Wnt signaling pathway Database 0.11
Category members GO Category GO:0045638 negative regulation of myeloid cell differentiation Database 0.1
Category members GO Category GO:0006378 mRNA polyadenylation Database 0.1
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0071222 cellular response to lipopolysaccharide Database 0


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