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Query: PAPOLA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAPOLA 1 3.761 -1.510 2.810

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PAPOLA Phosphorylation S40 0.114 1.106 _HYGITS(ph)PISLAAPK_
PAPOLA Phosphorylation S553 0.479 _LTALNDSSLDLSM(ox)DSDNSM(ox)SVPS(ph)PTSATK_
PAPOLA Phosphorylation T39 -0.241 0.026 _HYGIT(ph)SPISLAAPK_
PAPOLA Ubiquitylation K160 -0.269 _LQEEVK(gl)DLR_

Background Information for PAPOLA:


Pubmed-PAPOLA »
Uniprot-PAPOLA »
Biogrid-PAPOLA »
ProteomicsDB-PAPOLA »

Tumorportal-PAPOLA »
COSMIC-PAPOLA »
GenomeRNAi-PAPOLA »
Genecards-PAPOLA


Protein-protein Interactions for PAPOLA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PAPOLA Cat. description Hein, Mann, Cell 2015
Category members IP bait FGB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAPOLA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleotidyltransferase IPR002934 0.13
Category members PolA_pol_RNA-bd_dom IPR007010 0.11
Category members PolA_pol_cen_dom IPR007012 0.11
Category members NuclTrfase_I_C IPR011068 0.11
Category members PolyA_polymerase IPR014492 0.11


Protein complexes (CORUM database) featuring PAPOLA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5228 REL-MAP3K8-RELA-TNIP2-PAPOLA complex Database 0


Categories featuring PAPOLA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members Pathway Pathway_855 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS 0 0.29
Category members Pathway Pathway_310 KEGG_RNA_DEGRADATION 0 0.26
Category members GO Category GO:0006378 mRNA polyadenylation Database 0.1
Category members GO Category GO:0043631 RNA polyadenylation Database 0.1
Category members Pathway Pathway_853 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 0 0.05
Category members GO Category GO:0000287 magnesium ion binding Database 0
Category members GO Category GO:0004652 polynucleotide adenylyltransferase activity Database 0
Category members GO Category GO:0016779 nucleotidyltransferase activity Database 0
Category members GO Category GO:0030145 manganese ion binding Database 0
Category members GO Category GO:0031123 RNA 3'-end processing Database 0


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