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REACTOME_MRNA_3_END_PROCESSING
(Pathway_852)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PCF11 3 -2.050 3.820 0.235
PCF11 3 -2.050 3.820 -1.031 1.582 3.004 -1.330 -0.783
SRSF7 2 -0.690 0.700 -0.134 -0.453 -0.090 0.040 -0.277
PAPOLA 1 -1.510 2.810
SRSF3 1 -0.610 0.630 0.651 -0.506 -0.239 0.169 0.421
SRRM1 1 0.510 -1.020 -2.536 -0.548 -0.106
SRSF2 1 0.230 -0.340
SRSF2 1 0.230 -0.340 0.316 0.700 -0.680 -0.119 -0.358
CDC40 1 -1.360 3.020 1.080 -0.487 0.013
CLP1 1 1.560 -1.130 -2.044 -4.197
U2AF2 0 -0.290 1.210 0.056 0.174 -0.026
NFX1 0 -0.440 0.390
SRSF5 0 0.770 -0.700 0.220 1.031 0.250 0.325
SRSF5 0 0.770 -0.700
PABPN1 0 0.050 -0.870 0.188 -0.487 -0.009 0.323 0.510
CSTF1 0 0.350 -0.880 0.804 -0.169 0.601
CSTF2 0 -0.939 -0.663 0.068 -0.442 -0.123
SRSF9 0 1.320 -1.120
SRSF9 0 1.320 -1.120 0.129 -0.719 0.039 0.558 0.293
NCBP2 0 -0.700 0.840 0.520 0.032 1.096 -0.957
SRSF4 0 -0.950 1.920 0.189 -1.074 0.320 0.240 0.525
SRSF11 0 0.900 -0.210 -0.020 -0.348 -0.418 -0.267
SRSF11 0 0.900 -0.210
CPSF3 0 0.760 -0.720 -0.001 -0.206 0.455 -0.433 0.066
SRSF6 0 0.510 -0.580 0.873 0.221 0.612 0.582 0.508
UPF3B 0 -0.820 0.890 -0.652 -0.447
SRSF1 0 -1.250 2.260
SRSF1 0 -1.250 2.260 0.403 -0.228 0.177 0.550 0.395
NCBP1 0 -0.510 0.770 1.020 -0.130 0.769 -0.383 0.710
DHX38 0 1.472 -0.284 -0.034
CPSF7 0 0.850 -0.560 0.101 -0.052 -0.087 0.114 0.376
U2AF1 0 -0.080 -0.050 0.129 -0.015 0.165 0.219 0.101
MAGOH 0 0.620 -0.230 0.555 -0.780 0.144
MAGOH 0 0.620 -0.230 0.252 -0.826 -0.734 -0.871 -0.164
CPSF2 0 0.150 0.340 -0.113 -0.032 0.570 0.441 0.355
NUDT21 0 -0.700 0.830 0.214 -0.359 0.236 0.333 0.307
CSTF3 0 -1.060 1.590 -0.198 -0.392 0.251 -0.683 -0.064
RNPS1 0 -1.050 1.360 0.820 1.396 0.628 -0.117 0.102
RNPS1 0 -0.890 1.750 0.820 1.396 0.628 -0.117 0.102

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CDC40 Phosphorylation S43 -0.705 -0.097 _S(ph)PSSKPSLAVAVDSAPEVAVK_
CLP1 Ubiquitylation K138 1.918 0.745 _VMVVGPTDVGK(gl)STVCR_
CLP1 Ubiquitylation K292 0.258 0.199 _TVLLPK(gl)SGGVVER_
CPSF2 Ubiquitylation K140 -0.692 _FSQIVNLKGK(gl)_
CPSF2 Ubiquitylation K324 -1.406 -1.082 _VPSPK(gl)VVLASQPDLECGFSR_
CPSF2 Ubiquitylation K725 0.157 _LSDFK(gl)QVLLR_
CPSF3 Ubiquitylation K348 0.384 _ELFESWCTDK(gl)R_
CPSF3 Ubiquitylation K428 0.656 0.535 _LK(gl)AALIR_
CPSF3 Ubiquitylation K465 0.422 _NTEAVTLNFRGEKLAK(gl)_
CPSF3 Ubiquitylation K474 -0.536 _VMGFLADKK(gl)PEQGQR_
CPSF3 Ubiquitylation K487 0.072 0.155 _VSGILVK(gl)R_
CPSF3 Ubiquitylation K604 -0.159 _K(gl)LEMHVYSK_
CPSF7 Phosphorylation S48 -0.955 -1.077 _SSS(ph)TEPPPPVR_
CPSF7 Phosphorylation T203 -0.630 -1.317 _DSSDSADGRAT(ph)PSENLVPSSAR_
CSTF1 Ubiquitylation K208 0.139 _LFDYSKPSAK(gl)R_
CSTF1 Ubiquitylation K326 0.325 _YILSSGK(gl)DSVAK_
CSTF2 Ubiquitylation K55 -0.926 _LVYDRETGK(gl)PK_
CSTF2 Ubiquitylation K96 -0.716 _VDNAASEK(gl)NKEELK_
CSTF2 Ubiquitylation K98 -0.716 _VDNAASEK(gl)NKEELK_
CSTF2 Ubiquitylation K148 0.429 0.722 _QMK(gl)LCVQNSPQEAR_
CSTF2 Phosphorylation S538 -1.435 _QVPVMQGTGMQGASIQGGS(ph)QPGGFSPGQNQVTPQDHEK_
CSTF2 Ubiquitylation K592 -0.132 _EQIQK(gl)STGAP_
CSTF3 Phosphorylation S2 0.874 _(ac)S(ph)GDGATEQAAEYVPEK_
CSTF3 Ubiquitylation K17 -0.812 _(ac)SGDGATEQAAEYVPEK(gl)VK_
CSTF3 Ubiquitylation K19 -0.812 _(ac)SGDGATEQAAEYVPEK(gl)VK_
CSTF3 Ubiquitylation K49 -1.513 0.082 _EAQNQPIDK(gl)AR_
CSTF3 Phosphorylation S691 -0.393 -0.297 _RPNEDS(ph)DEDEEKGAVVPPVHDIYR_
MAGOH Ubiquitylation K16 0.886 _YYVGHK(gl)GK_
MAGOH Ubiquitylation K43 0.470 -0.293 _YANNSNYK(gl)NDVMIR_
MAGOH Ubiquitylation K63 0.752 1.122 _SVM(ox)EELK(gl)R_
MAGOH Ubiquitylation K116 -0.667 _IGSLIDVNQSK(gl)DPEGLR_
NCBP1 Phosphorylation T21 0.500 1.259 _KT(ph)SDANETEDHLESLICK_
NCBP1 Phosphorylation S22 1.091 1.381 _KTS(ph)DANETEDHLESLICK_
NCBP1 Ubiquitylation K204 0.269 _IFANTESYLK(gl)R_
NCBP2 Ubiquitylation K7 -1.025 _(ac)SGGLLK(gl)ALR_
NFX1 Phosphorylation S49 -0.096 -1.081 _NYS(ph)SPPPCHLSR_
NFX1 Phosphorylation S50 -0.613 -0.140 _NYSS(ph)PPPCHLSR_
NFX1 Phosphorylation S150 0.031 1.227 _SESGTDLREHS(ph)PSESEK_
NFX1 Phosphorylation S326 -0.780 _RQDPQVVS(ph)PFSR_
NUDT21 Ubiquitylation K29 -0.121 -0.076 _YIQQTK(gl)PLTLER_
NUDT21 Ubiquitylation K56 -1.058 0.450 _EPLYEK(gl)DSSVAAR_
NUDT21 Ubiquitylation K73 0.158 _MREEFDK(gl)IGMR_
NUDT21 Ubiquitylation K122 -1.445 _LPGGELNPGEDEVEGLK(gl)R_
NUDT21 Ubiquitylation K189 -0.510 _ALFAVPK(gl)NYK_
NUDT21 Ubiquitylation K192 -0.730 -0.836 _ALFAVPKNYK(gl)_
PABPN1 Phosphorylation S19 0.994 _(ac)AAAAAAAAAAGAAGGRGS(ph)GPGR_
PABPN1 Phosphorylation S95 0.073 -0.826 _APPGAPGPGPGSGAPGS(ph)QEEEEEPGLVEGDPGDGAIEDPELEAIK_
PABPN1 Ubiquitylation K137 1.020 _LK(gl)ELQNEVEK_
PABPN1 Phosphorylation S150 -0.197 _QMNMS(ph)PPPGNAGPVIMSIEEK_
PABPN1 Ubiquitylation K207 0.137 1.327 _VTILCDK(gl)FSGHPK_
PAPOLA Phosphorylation T39 -0.241 0.026 _HYGIT(ph)SPISLAAPK_
PAPOLA Phosphorylation S40 0.114 1.106 _HYGITS(ph)PISLAAPK_
PAPOLA Ubiquitylation K160 -0.269 _LQEEVK(gl)DLR_
PAPOLA Phosphorylation S553 0.479 _LTALNDSSLDLSM(ox)DSDNSM(ox)SVPS(ph)PTSATK_
PCF11 Phosphorylation S494 0.108 0.338 _SPIIHS(ph)PK_
PCF11 Phosphorylation S705 -0.513 -0.572 _EEQRS(ph)PFNDRFPLK_
PCF11 Phosphorylation S800 0.255 0.405 _RLS(ph)PISGSR_
PCF11 Ubiquitylation K1278 0.074 _LLK(gl)TGILK_
PCF11 Phosphorylation T1530 -0.702 -0.561 _IDT(ph)PPACTEESIATPSEIK_
RNPS1 Ubiquitylation K8 -0.465 _(ac)MDLSGVKK(gl)_
RNPS1 Phosphorylation S251 0.028 _RFS(ph)PPRR_
SRRM1 Ubiquitylation K36 -0.052 _FAECLEK(gl)K_
SRRM1 Ubiquitylation K37 0.946 -0.052 _FAECLEKK(gl)_
SRRM1 Phosphorylation T220 -0.236 -0.247 _T(ph)PELPEPSVK_
SRRM1 Phosphorylation S234 0.189 0.288 _VKEPS(ph)VQEATSTSDILK_
SRRM1 Phosphorylation S260 -1.874 -1.702 _VPKPEPIPEPKEPS(ph)PEK_
SRRM1 Phosphorylation S389 0.530 -0.508 _RLS(ph)PS(ph)ASPPR_
SRRM1 Phosphorylation S391 0.670 1.010 _RLS(ph)PS(ph)ASPPR_
SRRM1 Phosphorylation S393 0.180 0.278 _RLS(ph)PSAS(ph)PPR_
SRRM1 Phosphorylation S402 -0.216 -0.477 _HRPS(ph)PPAT(ph)PPPK_
SRRM1 Phosphorylation T406 -1.669 -1.607 _HRPS(ph)PPAT(ph)PPPK_
SRRM1 Phosphorylation S448 -0.669 -0.441 _RES(ph)PSPAPKPR_
SRRM1 Phosphorylation S450 -0.294 _RESPS(ph)PAPKPR_
SRRM1 Phosphorylation S461 0.912 0.886 _KVELS(ph)ESEEDKGGK_
SRRM1 Phosphorylation S463 2.082 0.890 _KVELSES(ph)EEDKGGK_
SRRM1 Phosphorylation S550 0.523 0.207 _RWQS(ph)PVTK_
SRRM1 Phosphorylation S609 0.257 0.339 _RYS(ph)PPIQR_
SRRM1 Phosphorylation S617 -0.202 -0.195 _RYS(ph)PS(ph)PPPK_
SRRM1 Phosphorylation S619 -0.637 -0.652 _RYS(ph)PS(ph)PPPK_
SRRM1 Phosphorylation T626 -1.225 -0.870 _T(ph)AS(ph)PPPPPK_
SRRM1 Phosphorylation S628 -0.806 -0.787 _T(ph)AS(ph)PPPPPK_
SRRM1 Phosphorylation S706 -0.527 -0.615 _APQTS(ph)SSPPPVRR_
SRRM1 Phosphorylation S707 -0.548 -0.489 _APQTSS(ph)SPPPVR_
SRRM1 Phosphorylation S708 -0.506 -0.481 _APQTSSS(ph)PPPVRR_
SRRM1 Phosphorylation S725 0.842 0.451 _RQS(ph)PSPSTRPIR_
SRRM1 Phosphorylation S727 0.068 0.089 _RQSPS(ph)PSTRPIR_
SRRM1 Phosphorylation S729 0.141 -0.253 _QS(ph)PSPS(ph)TRPIRR_
SRRM1 Phosphorylation T730 -0.345 -0.119 _RQSPSPST(ph)RPIR_
SRRM1 Phosphorylation S750 0.336 0.368 _AAS(ph)PSPQSVR_
SRRM1 Phosphorylation S752 0.546 0.509 _KAAS(ph)PS(ph)PQSVR_
SRRM1 Phosphorylation S781 -1.190 -1.298 _KPPAPPS(ph)PVQSQSPSTNWSPAVPVK_
SRRM1 Phosphorylation S785 -1.558 -1.554 _KPPAPPS(ph)PVQS(ph)QSPSTNWSPAVPVK_
SRRM1 Phosphorylation S787 -0.948 -1.602 _KPPAPPS(ph)PVQSQS(ph)PSTNWSPAVPVK_
SRRM1 Phosphorylation S789 -0.821 _KPPAPPS(ph)PVQSQSPS(ph)TNWSPAVPVKK_
SRRM1 Phosphorylation T884 0.984 0.756 _KET(ph)ES(ph)EAEDNLDDLEK_
SRRM1 Phosphorylation S886 0.612 0.556 _KET(ph)ES(ph)EAEDNLDDLEK_
SRSF1 Ubiquitylation K30 0.295 1.069 _TK(gl)DIEDVFYK_
SRSF1 Ubiquitylation K38 -0.206 _DIEDVFYK(gl)YGAIR_
SRSF1 Ubiquitylation K48 0.753 _DIDLK(gl)NRR_
SRSF1 Ubiquitylation K138 -0.322 _VVVSGLPPSGSWQDLK(gl)DHMR_
SRSF1 Ubiquitylation K165 0.718 _K(gl)EDMTYAVR_
SRSF1 Ubiquitylation K174 0.393 _K(gl)LDNTK(gl)FR_
SRSF1 Ubiquitylation K179 0.296 _K(gl)LDNTK(gl)FR_
SRSF1 Phosphorylation S199 0.467 0.632 _VDGPRS(ph)PS(ph)YGR_
SRSF1 Phosphorylation S201 0.651 0.628 _VDGPRS(ph)PS(ph)YGR_
SRSF11 Phosphorylation S207 1.471 0.818 _LNHVAAGLVS(ph)PSLK_
SRSF11 Ubiquitylation K217 0.182 _SDTSSK(gl)EIEEAMKR_
SRSF11 Ubiquitylation K224 0.596 _EIEEAMK(gl)R_
SRSF11 Phosphorylation T325 0.481 0.548 _SKT(ph)PPKSYSTAR_
SRSF11 Phosphorylation S338 1.228 0.953 _S(ph)ASSLHICDSR_
SRSF11 Phosphorylation Y432 0.735 _DYDEEEQGY(ph)DSEKEK_
SRSF11 Phosphorylation S434 0.689 0.734 _DYDEEEQGYDS(ph)EKEKK_
SRSF11 Phosphorylation T447 -0.188 _KPIET(ph)GSPK_
SRSF11 Phosphorylation S449 -0.226 0.188 _KPIETGS(ph)PK_
SRSF11 Phosphorylation S456 0.873 0.882 _TKECS(ph)VEKGTGDSLR_
SRSF2 Phosphorylation S2 -0.541 0.173 _(ac)S(ph)YGRPPPDVEGMTSLK_
SRSF2 Phosphorylation T22 0.740 0.763 _VDNLT(ph)YRTSPDTLR_
SRSF2 Phosphorylation T25 0.781 0.654 _VDNLTYRT(ph)SPDTLR_
SRSF2 Phosphorylation S26 0.636 0.891 _VDNLTYRTS(ph)PDTLR_
SRSF2 Phosphorylation T29 0.970 _VDNLTYRTSPDT(ph)LR_
SRSF2 Ubiquitylation K63 1.341 1.921 _VFEK(gl)YGR_
SRSF2 Phosphorylation S182 -0.171 -0.115 _SKS(ph)PPKSPEEEGAVSS_
SRSF3 Phosphorylation S5 0.331 0.430 _(ac)MHRDS(ph)CPLDCK_
SRSF3 Ubiquitylation K23 1.262 3.212 _VYVGNLGNNGNK(gl)TELER_
SRSF3 Ubiquitylation K85 1.015 _VRVELSNGEK(gl)R_
SRSF4 Phosphorylation S431 0.473 0.519 _EGRGES(ph)ENAGTNQETR_
SRSF4 Phosphorylation S456 0.062 0.006 _SKPNLPS(ph)ESR_
SRSF4 Phosphorylation S458 0.989 _SKPNLPS(ph)ESR_
SRSF5 Phosphorylation S287 -0.002 _SVSRS(ph)PVPEK_
SRSF6 Ubiquitylation K101 0.427 _DK(gl)YGPPVR_
SRSF6 Ubiquitylation K143 0.804 _QAGEVTYADAHK(gl)ER_
SRSF6 Ubiquitylation K165 0.740 _ALDK(gl)LDGTEINGR_
SRSF6 Phosphorylation S303 -0.953 -0.594 _SNS(ph)PLPVPPSK_
SRSF7 Ubiquitylation K12 1.581 _YGGETK(gl)VYVGNLGTGAGK_
SRSF7 Ubiquitylation K24 0.588 0.481 _VYVGNLGTGAGK(gl)GELER_
SRSF7 Ubiquitylation K70 1.291 2.646 _GLDGK(gl)VICGSR_
SRSF7 Phosphorylation S192 0.600 0.679 _YFQS(ph)PSR_
SRSF9 Ubiquitylation K36 -0.611 _DLEDLFYK(gl)YGR_
SRSF9 Ubiquitylation K46 0.282 -0.099 _IREIELK(gl)NR_
SRSF9 Ubiquitylation K155 0.178 _K(gl)EDMEYALR_
SRSF9 Ubiquitylation K164 0.059 -0.489 _K(gl)LDDTKFR_
SRSF9 Ubiquitylation K169 -0.590 _KLDDTK(gl)FR_
SRSF9 Phosphorylation S189 1.014 0.830 _STS(ph)YGYSR_
SRSF9 Phosphorylation S193 0.905 0.880 _STSYGYS(ph)R_
SRSF9 Phosphorylation S204 0.206 _GRDS(ph)PYQSR_
SRSF9 Phosphorylation S211 0.094 -0.013 _GS(ph)PHYFS(ph)PFRPY_
SRSF9 Phosphorylation Y214 0.011 0.021 _GSPHY(ph)FSPFRPY_
SRSF9 Phosphorylation S216 -0.026 -1.018 _GS(ph)PHYFS(ph)PFRPY_
U2AF1 Ubiquitylation K15 0.020 _DK(gl)VNCSFYFK_
U2AF2 Phosphorylation S2 0.658 0.706 _(ac)S(ph)DFDEFER_
U2AF2 Ubiquitylation K70 0.614 _GAK(gl)EEHGGLIR_
U2AF2 Phosphorylation S79 -0.077 0.135 _GAKEEHGGLIRS(ph)PR_
U2AF2 Ubiquitylation K462 0.048 _VVVTK(gl)YCDPDSYHR_
UPF3B Ubiquitylation K196 0.208 _K(gl)TTPLLSFLK_


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