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Query: NCBP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NCBP1 0 4.858 -0.510 0.770 1.020 -0.130 0.769 -0.383 0.710

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NCBP1 Phosphorylation S22 1.091 1.381 _KTS(ph)DANETEDHLESLICK_
NCBP1 Phosphorylation T21 0.500 1.259 _KT(ph)SDANETEDHLESLICK_
NCBP1 Ubiquitylation K204 0.269 _IFANTESYLK(gl)R_

Background Information for NCBP1:


Pubmed-NCBP1 »
Uniprot-NCBP1 »
Biogrid-NCBP1 »
ProteomicsDB-NCBP1 »

Tumorportal-NCBP1 »
COSMIC-NCBP1 »
GenomeRNAi-NCBP1 »
Genecards-NCBP1


Protein-protein Interactions for NCBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BOD1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait CERK Cat. description Hein, Mann, Cell 2015
Category members IP bait DENND6A Cat. description Hein, Mann, Cell 2015
Category members IP bait FERMT3 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH3 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PHAX Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM7 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait USO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ZNF187 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GSPT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NCBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members MIF4G-like_typ-3 IPR003890 0


Protein complexes (CORUM database) featuring NCBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1176 CRM1-RAN-PHAX-CBC complex (cap binding complex) Database 0.57
Category members Corum 1174 PHAX-CBC complex (cap binding complex) Database 0.04
Category members Corum 1172 CBC complex (cap binding complex) Database 0
Category members Corum 1190 NCBP-NIP1 complex Database 0
Category members Corum 775 CBC complex (cap binding complex) Database 0


Categories featuring NCBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016032 viral process Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_197 REACTOME_HIV_INFECTION 0 12.07
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_376 REACTOME_HIV_LIFE_CYCLE 0 9.45
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members Pathway Pathway_374 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE 0 7.57
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members Pathway Pathway_886 REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT 0 5.93
Category members GO Category GO:0050434 positive regulation of viral transcription Database 4.8
Category members Pathway Pathway_887 REACTOME_METABOLISM_OF_NON_CODING_RNA 0 4.38
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_360 REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ 0 3.35
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members GO Category GO:0006368 transcription elongation from RNA polymerase II promoter Database 2.03
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members Pathway Pathway_363 REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS 0 1.84
Category members GO Category GO:0051028 mRNA transport Database 1.7
Category members Pathway Pathway_361 REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX 0 1.57
Category members Pathway Pathway_362 REACTOME_MRNA_CAPPING 0 1.57
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0006370 7-methylguanosine mRNA capping Database 1.26
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0031442 positive regulation of mRNA 3'-end processing Database 0.7
Category members Pathway Pathway_364 REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT 0 0.35
Category members Pathway Pathway_855 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS 0 0.29
Category members Pathway Pathway_853 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 0 0.05
Category members GO Category GO:0000387 spliceosomal snRNP assembly Database 0.04
Category members GO Category GO:0006446 regulation of translational initiation Database 0.04
Category members Pathway Pathway_885 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS 0 0
Category members GO Category GO:0000339 RNA cap binding Database 0
Category members GO Category GO:0005845 mRNA cap binding complex Database 0
Category members GO Category GO:0005846 nuclear cap binding complex Database 0
Category members GO Category GO:0006379 mRNA cleavage Database 0
Category members GO Category GO:0008334 histone mRNA metabolic process Database 0
Category members GO Category GO:0031047 gene silencing by RNA Database 0
Category members GO Category GO:0034660 ncRNA metabolic process Database 0
Category members GO Category GO:0045292 mRNA cis splicing, via spliceosome Database 0


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