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Query: RNPS1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNPS1 0 4.142 -1.050 1.360 0.820 1.396 0.628 -0.117 0.102
RNPS1 0 4.142 -0.890 1.750 0.820 1.396 0.628 -0.117 0.102

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNPS1 Phosphorylation S251 0.028 _RFS(ph)PPRR_
RNPS1 Ubiquitylation K8 -0.465 _(ac)MDLSGVKK(gl)_

Background Information for RNPS1:


Pubmed-RNPS1 »
Uniprot-RNPS1 »
Biogrid-RNPS1 »
ProteomicsDB-RNPS1 »

Tumorportal-RNPS1 »
COSMIC-RNPS1 »
GenomeRNAi-RNPS1 »
Genecards-RNPS1


Protein-protein Interactions for RNPS1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PDGFRA Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C11orf57 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CAMKV Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX41 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENND2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELAVL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLHL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LUC7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NKAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPF40A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTGER3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SARNP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNIP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRNP70 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SRPK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait U2AF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UPF3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WSB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZCCHC17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in RNPS1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members REJ-like IPR014010 0


Protein complexes (CORUM database) featuring RNPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 760 Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18-RNPS1-Acinus-L Database 0.57
Category members Corum 761 Apoptosis- and splicing-associated protein complex (ASAP-S), SAP18-RNPS1-Acinus-S Database 0.57
Category members Corum 5449 Splicing-associated factors complex Database 0.5
Category members Corum 785 Exon junction complex Database 0.29
Category members Corum 814 Postsplicing complex Database 0.01


Categories featuring RNPS1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_770 REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX 0 INF
Category members Pathway Pathway_771 REACTOME_METABOLISM_OF_RNA 0 INF
Category members Pathway Pathway_773 REACTOME_METABOLISM_OF_MRNA 0 INF
Category members GO Category GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0016071 mRNA metabolic process Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0048025 negative regulation of mRNA splicing, via spliceosome Database 2.79
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0061574 ASAP complex Database 0.57
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members GO Category GO:0035145 exon-exon junction complex Database 0.28
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0003730 mRNA 3'-UTR binding Database 0.24


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