bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: CPSF7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CPSF7 0 -1.203 0.850 -0.560 0.101 -0.052 -0.087 0.114 0.376

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CPSF7 Phosphorylation S48 -0.955 -1.077 _SSS(ph)TEPPPPVR_
CPSF7 Phosphorylation T203 -0.630 -1.317 _DSSDSADGRAT(ph)PSENLVPSSAR_

Background Information for CPSF7:


Pubmed-CPSF7 »
Uniprot-CPSF7 »
Biogrid-CPSF7 »
ProteomicsDB-CPSF7 »

Tumorportal-CPSF7 »
COSMIC-CPSF7 »
GenomeRNAi-CPSF7 »
Genecards-CPSF7


Protein-protein Interactions for CPSF7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC93 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait CPSF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait NUDT21 Cat. description Hein, Mann, Cell 2015
Category members IP bait PFKFB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC16A Cat. description Hein, Mann, Cell 2015
Category members IP bait BCHE Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CPSF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JMJD6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CPSF7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34


Protein complexes (CORUM database) featuring CPSF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1141 CF IIAm complex (Cleavage factor IIAm complex) Database 2.57


Categories featuring CPSF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0051262 protein tetramerization Database 0.6
Category members Pathway Pathway_855 REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS 0 0.29
Category members GO Category GO:0005849 mRNA cleavage factor complex Database 0.13
Category members Pathway Pathway_853 REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA 0 0.05


.

© Copyright Svejstrup Laboratory 2015