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Query: SRSF6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRSF6 0 1.220 0.510 -0.580 0.873 0.221 0.612 0.582 0.508

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRSF6 Phosphorylation S303 -0.953 -0.594 _SNS(ph)PLPVPPSK_
SRSF6 Ubiquitylation K101 0.427 _DK(gl)YGPPVR_
SRSF6 Ubiquitylation K143 0.804 _QAGEVTYADAHK(gl)ER_
SRSF6 Ubiquitylation K165 0.740 _ALDK(gl)LDGTEINGR_

Background Information for SRSF6:


Pubmed-SRSF6 »
Uniprot-SRSF6 »
Biogrid-SRSF6 »
ProteomicsDB-SRSF6 »

Tumorportal-SRSF6 »
COSMIC-SRSF6 »
GenomeRNAi-SRSF6 »
Genecards-SRSF6


Protein-protein Interactions for SRSF6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015


Protein Domains in SRSF6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members RRM_3 IPR014886 0


Protein complexes (CORUM database) featuring SRSF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 2589 PGC-1-SRp40-SRp55-SRp75 complex Database 0.07


Categories featuring SRSF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0048025 negative regulation of mRNA splicing, via spliceosome Database 2.79
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0006376 mRNA splice site selection Database 0.63
Category members GO Category GO:0000381 regulation of alternative mRNA splicing, via spliceosome Database 0.5
Category members GO Category GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0


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