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Query: SRSF7

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SRSF7 2 5.835 -0.690 0.700 -0.134 -0.453 -0.090 0.040 -0.277

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SRSF7 Ubiquitylation K70 1.291 2.646 _GLDGK(gl)VICGSR_
SRSF7 Phosphorylation S192 0.600 0.679 _YFQS(ph)PSR_
SRSF7 Ubiquitylation K24 0.588 0.481 _VYVGNLGTGAGK(gl)GELER_
SRSF7 Ubiquitylation K12 1.581 _YGGETK(gl)VYVGNLGTGAGK_

Background Information for SRSF7:


Pubmed-SRSF7 »
Uniprot-SRSF7 »
Biogrid-SRSF7 »
ProteomicsDB-SRSF7 »

Tumorportal-SRSF7 »
COSMIC-SRSF7 »
GenomeRNAi-SRSF7 »
Genecards-SRSF7


Protein-protein Interactions for SRSF7
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MZT1 Cat. description Hein, Mann, Cell 2015


Protein Domains in SRSF7
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members Znf_CCHC IPR001878 1.51


Protein complexes (CORUM database) featuring SRSF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1068 12S U11 snRNP Database 0.17


Categories featuring SRSF7
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0000398 mRNA splicing, via spliceosome Database 7.06
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0006406 mRNA export from nucleus Database 4.09
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0048025 negative regulation of mRNA splicing, via spliceosome Database 2.79
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members Pathway Pathway_372 REACTOME_MRNA_SPLICING_MINOR_PATHWAY 0 1.52
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0031124 mRNA 3'-end processing Database 0.91
Category members GO Category GO:0006369 termination of RNA polymerase II transcription Database 0.87
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008270 zinc ion binding Database 0.29


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