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Query: NFX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
NFX1 0 1.648 -0.440 0.390

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
NFX1 Phosphorylation S150 0.031 1.227 _SESGTDLREHS(ph)PSESEK_
NFX1 Phosphorylation S50 -0.613 -0.140 _NYSS(ph)PPPCHLSR_
NFX1 Phosphorylation S326 -0.780 _RQDPQVVS(ph)PFSR_
NFX1 Phosphorylation S49 -0.096 -1.081 _NYS(ph)SPPPCHLSR_

Background Information for NFX1:


Pubmed-NFX1 »
Uniprot-NFX1 »
Biogrid-NFX1 »
ProteomicsDB-NFX1 »

Tumorportal-NFX1 »
COSMIC-NFX1 »
GenomeRNAi-NFX1 »
Genecards-NFX1


Protein-protein Interactions for NFX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FAM46A Cat. description Hein, Mann, Cell 2015
Category members IP bait APBA3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF263 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in NFX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_PHD-finger IPR019787 0.91
Category members Znf_NFX1 IPR000967 0
Category members R3H_ss-bd IPR001374 0
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring NFX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring NFX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_373 REACTOME_MRNA_PROCESSING 0 12.92
Category members Pathway Pathway_380 REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA 0 12.24
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_377 REACTOME_MRNA_SPLICING 0 6.99
Category members Pathway Pathway_878 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM 0 6.53
Category members Pathway Pathway_375 REACTOME_RNA_POL_II_TRANSCRIPTION 0 2.46
Category members Pathway Pathway_852 REACTOME_MRNA_3_END_PROCESSING 0 2.02
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members Pathway Pathway_854 REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ 0 0.91
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0006954 inflammatory response Database 0.49
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0045347 negative regulation of MHC class II biosynthetic process Database 0.01
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016874 ligase activity Database 0


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